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Chiyoda : Development of Large-scale Production Technology for Useful Proteins Using PlantsLaunch of a 'Plant Biofoundry' - a Demonstration Platform in the Field of Bio-manufacturing
Chiyoda : Development of Large-scale Production Technology for Useful Proteins Using PlantsLaunch of a 'Plant Biofoundry' - a Demonstration Platform in the
About this update from Chiyoda Corp.
[{"type":"text","content":"\n PRESS RELEASE\n \n \n \n July 7, 2025\n \n \n \n Chiyoda Corporation New Energy and Industrial Technology Development Organization (NEDO)\n \n \n \n Development of Large-scale Production Technology for Useful Proteins Using Plants\n \n \n Launch of a 'Plant Biofoundry' - a Demonstration Platform in the Field of Bio-manufacturing\n \n \n \n Chiyoda Corporation (Chiyoda) has successfully developed foundational technology for producing useful substances using plants, as part of NEDO's project 'Development of Bio-derived Product Production Technology to Accelerate Carbon Recycling'. The project demonstrates the production of human type II collagen, the first of its kind globally, as a model protein for the production of useful substances. Utilizing plants allows for animal-free and cost-effective production of products, such as vaccines, pharmaceuticals, regenerative medicine products, cosmetics and functional foods, while reducing greenhouse gas emissions.\n \n \n This facility, Japan's first 'Plant Biofoundry', is dedicated to the practical development of plant bio-manufacturing and will support research and development from third party institutions and companies. This will be showcased at Chiyoda's booth during the 'INTERPHEX Week Tokyo / Regenerative Medicine EXPO Tokyo' held at Tokyo Big Sight from 9 to 11 July, 2025.\n \n \n Figure 1: Exterior of the Plant Bio Demonstration Facility and Plants Under Cultivation\n Background\n \n \n The technology for producing materials using living organisms such as plants and microorganisms (bio-manufacturing) is more energy-efficient and does not rely on fossil resources. It is expected to transform manufacturing that contribute to a carbon-circular society and sustainable economic growth. Challenges remain however, including lower production efficiency compared to petroleum-derived products and inferior physical properties of bio-products.\n \n \n \n While foundational technology demonstration facilities have been established for the production of useful substances using microorganisms, producing complex molecules with high molecular weights, such as those requiring post-translational modifications, is challenging with microorganisms. Conversely, plants are expected to enable the production of such useful substances, necessitating the urgent establishment of foundational technology demo...