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Presidential Executive Order Validates DeFloria's Strategy in Pharmaceutical Cannabinoid Drug Development

Presidential Executive Order Validates DeFloria's Strategy in Pharmaceutical Cannabinoid Drug Dev...

articleCharlotte's Web Holdings, Inc.December 19, 20254/company/charlottes-web-holdings-inc/news/presidential-executive-order-validates-deflorias-strategy-in-pharmaceutical-cannabinoid-drug-development
Presidential Executive Order Validates DeFloria's Strategy in Pharmaceutical Cannabinoid Drug Development

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[{"type":"text","content":"\n\n\nPresidential Executive Order Validates DeFloria's Strategy in Pharmaceutical Cannabinoid Drug Development\n\n/* Style Definitions */\nspan.prnews_span\n{\nfont-size:8pt;\nfont-family:\"Arial\";\ncolor:black;\n}\na.prnews_a\n{\ncolor:blue;\n}\nli.prnews_li\n{\nfont-size:8pt;\nfont-family:\"Arial\";\ncolor:black;\n}\np.prnews_p\n{\nfont-size:0.62em;\nfont-family:\"Arial\";\ncolor:black;\nmargin:0in;\n}\n.prnml40{\nMARGIN-LEFT:3.33em !IMPORTANT\n}\n.prntac{\nTEXT-ALIGN: CENTER\n}\n\n\n\n\n\nCanada NewsWire\n\n\nDeFloria Advancing Charlotte's Web Legacy as Pioneer in Cannabinoid Health, with Phase 2 Clinical Trials for Autism Botanical Drug\nLOUISVILLE, Colo. and WASHINGTON, Dec. 19, 2025 /CNW/ - DeFloria Inc., a botanical drug development Company recognizes the Presidential Executive Order to reclassify cannabis from Schedule I to Schedule III, as a critical accelerator for cannabinoid medical innovation and regulatory reform. DeFloria is advancing a leading cannabinoid-based investigational new drug (\"IND\") through the FDA botanical drug pathway for autism-related irritability (AJA001 oral solution). The Executive Order represents pivotal federal acknowledgment of the therapeutic value of cannabinoids and validates a patient-centered movement that began more than a decade ago with the Stanley Brothers and their founding of Charlotte's Web (TSX: CWEB) (OTCQB: CWBHF).\n\n\n\n\n\n\n\n\"Charlotte's Web ignited the era of cannabinoid medicine, and DeFloria is the next chapter, elevating that mission with scientific rigor and FDA pathways,\" said Joel Stanley, Co-Founder of Charlotte's Web and Chair of the DeFloria Board. \"Federal policy is finally catching up to what patients, academics, and clinicians have long understood: cannabinoids hold real therapeutic power. DeFloria exists to transform that promise into approved medicines that change lives.\"\nBorn from the founders of Charlotte's Web - the market leading brand that defined CBD and reshaped the national dialogue - DeFloria is leveraging years of real-world medicinal benefits and patient experience that sparked the early momentum that led to this moment. Building on legacy and data, DeFloria is driving an entirely new category of FDA-regulated botanical drug development.\nFounders' Long-Standing Vision Gains Historic Federal Level Validation\nYears before federal p...

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