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CervoMed to Provide Neflamapimod Clinical Program Update and Participate in a Panel on Biomarkers at 2026 Lewy Body Dementia Association Annual Meeting
Update will include new MRI analyses from the Phase 2b RewinD-LB clinical trial, status of global regulatory discussions, and finalized Phase 3 trial design
About this update from Cervomed Inc.
[{"type":"text","content":"Update will include new MRI analyses from the Phase 2b RewinD-LB clinical trial, status of global regulatory discussions, and finalized Phase 3 trial design Additional data from MRI analyses will also be featured at 2026 American Academy of Neurology Annual Meeting later this month; findings demonstrate neflamapimod’s potential positive impact on basal forebrain atrophy and functional connectivity Dementia with Lewy bodies (DLB) is the second most common progressive dementia, affecting millions worldwide, and has no approved treatments in the United States or European Union BOSTON, April 07, 2026 (GLOBE NEWSWIRE) -- CervoMed Inc. (NASDAQ: CRVO) (CervoMed or the Company), a clinical-stage biotechnology company developing treatments for age-related brain disorders, will present key aspects of its neflamapimod clinical program today at the 2026 Lewy Body Dementia Association Annual Meeting in Atlanta, GA, including updates on the program’s clinical findings, global regulatory alignment, and finalized Phase 3 trial design in DLB. “We’re excited to share our progress across critical aspects of the neflamapimod program with the DLB community, including our alignment with global regulatory authorities on the planned neflamapimod Phase 3 trial, completion of the study’s design, and new encouraging analyses from the Phase 2 program,” said Matthew Winton, Ph.D., Chief Commercial and Business Officer of CervoMed. “The opportunity to potentially bring the first approved DLB treatment to patients and their families inspires us every day, and we look forward to working with the DLB community as we move forward with our planned Phase 3 trial.” \"In the absence of Alzheimer's disease (AD) co-pathology, disease expression and progression in DLB is largely driven by synaptic dysfunction, rather than neurodegeneration and neuronal loss, as is the case in AD, particularly AD dementia,” said John J. Alam, MD, Chief Executive Officer of CervoMed, who is participating in an expert panel discussion on the use of biomarkers in DLB clinical trials. \"As a result, a blood biomarker such as plasma glial fibrillary acidic protein (GFAP), that tracks with synaptic dysfunction, is the first blood biomarker that is elevated in the DLB disease course and correlates well with cognitive decline and clinical progression in patients. In our clinical studies, plasma...