Business
CervoMed Reports Second Quarter 2024 Financial Results and Provides Corporate Updates
- Completed enrollment in its RewinD-LB Phase 2b clinical trial evaluating neflamapimod in patients with early-stage dementia with Lewy bodies (DLB) in June
About this update from Cervomed Inc.
[{"type":"text","content":"- Completed enrollment in its RewinD-LB Phase 2b clinical trial evaluating neflamapimod in patients with early-stage dementia with Lewy bodies (DLB) in June 2024; topline data expected in December 2024 - - Hosted a virtual key opinion leader event in July 2024 highlighting neflamapimod’s potential for patients with early-stage DLB – - Completed private placement for up to $149.4 million of potential proceeds with leading institutional healthcare investors in April 2024 – - Added to the Russell 2000® and Russell 3000® Indexes effective July 1, 2024, as part of the 2024 Russell U.S. Indexes annual reconstitution - BOSTON, Aug. 12, 2024 (GLOBE NEWSWIRE) -- CervoMed Inc. (NASDAQ: CRVO), a clinical stage company focused on developing treatments for age-related neurologic disorders, today reported its financial results for the second quarter ended June 30, 2024. “In the second quarter, we continued to deliver on key milestones, highlighted by completing enrollment in RewinD-LB, our Phase 2b trial evaluating neflamapimod in patients with early-stage DLB, and we remain on track to report topline data from the study in December 2024,” said John Alam, MD, Chief Executive Officer of CervoMed. “Approximately two-thirds of the patients screened met the exclusion criteria for plasma ptau181—that is, they did not have advanced DLB—affirming our expectation that half or more of individuals with diagnosed DLB are still in the early stages of their disease. This, together with the high level of engagement across our clinical trial sites and the execution of our clinical team and partners, contributed to our ability to complete enrollment as planned. We look forward to building on the encouraging data from our Phase 2a AscenD-LB trial demonstrating neflamapimod’s potential to improve the lives of patients by targeting synaptic dysfunction in the basal forebrain cholinergic system to address cognitive, functional and motor aspects of the disease, and we believe a positive result in RewinD-LB will bring us one step closer to the market in this high value indication. Beyond DLB, we continue to explore additional opportunities to capitalize on neflamapimod’s potential to overcome existing challenges in neurological disorders driven by cholinergic dysfunction. This includes progressing early-stage clinical activities evaluating neflamapimod’s potential...