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Century Therapeutics Announces Presentation of Preclinical Data at the SITC 37th Annual Meeting and Provides Pipeline Updates
- Preclinical data support next generation platform for iPSC-derived NK cells with multiple gene edits to improve persistence and anti-tumor efficacy - -
About this update from Century Therapeutics, Inc.
[{"type":"text","content":"- Preclinical data support next generation platform for iPSC-derived NK cells with multiple gene edits to improve persistence and anti-tumor efficacy - - iPSC-derived CAR gamma delta T cells shown to effectively control solid tumors as monotherapy and in combination with a therapeutic antibody - - Company announces nomination of next pipeline program, CNTY-107 a Nectin-4 CAR gamma delta iT product candidate - - Company to host virtual Research and Development Day today at 8:00 AM ET - PHILADELPHIA, Nov. 11, 2022 (GLOBE NEWSWIRE) -- Century Therapeutics (NASDAQ: IPSC), an innovative biotechnology company developing induced pluripotent stem cell (iPSC)-derived cell therapies in immuno-oncology, today announced preclinical data from the Company’s iPSC-based cell therapy platform were featured in two posters at the Society for Immunotherapy of Cancer (SITC) 37th Annual Meeting. Additionally, the Company provided pipeline program updates ahead of its virtual Research and Development (R&D) Day taking place today, November 11, at 8:00 AM ET. “Developing a best-in-class iPSC derived gamma delta CAR T cell platform is a top priority at Century and we are excited to share additional data supporting our strategic decision to leverage this platform to address the complexities of solid tumors,” said Lalo Flores, Ph.D., Chief Executive Officer, Century Therapeutics. “Accordingly, we are pleased to announce the nomination of our newest pipeline program for solid tumors, CNTY-107, a Nectin-4 targeted gamma delta iT cell product candidate for which we expect to file an IND in 2025. Additionally, we continue to make progress with our iNK cell platform and are pleased to add to the preclinical data package supporting our iNK 3.0 platform, which shows enhanced functionality and illustrates the power and efficiencies of our platform. We look forward to discussing these updates later this morning during our virtual R&D Day.” Data Presented at SITC Annual Meeting and Pipeline Updates A copy of each poster presentation from the SITC Annual Meeting is available on Century’s website. Gamma Delta iT Cell Platform Gamma delta (γδ) T cells have been shown to exhibit the cytolytic features of conventional alpha beta (αβ) CD8+ T cells with additional capabilities for innate recognition of tumors and lack the risk for graft-versus-host-disease compared to αβ T...