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Century Therapeutics Announces Presentation of Data at the 63rd American Society of Hematology Annual Meeting and Provides Pipeline Updates

- In vivo data presented at ASH Annual Meeting demonstrated strong antitumor activity against human lymphoma cell lines with CNTY-101 - - Company announces

articleCentury Therapeutics, Inc.December 16, 20213/company/century-therapeutics-inc/news/century-therapeutics-announces-presentation-of-data-at-the-63rd-american-society-of-hematology-annual-meeting-and-provides-pipeline-updates
Century Therapeutics Announces Presentation of Data at the 63rd American Society of Hematology Annual Meeting and Provides Pipeline Updates

About this update from Century Therapeutics, Inc.

[{"type":"text","content":"- In vivo data presented at ASH Annual Meeting demonstrated strong antitumor activity against human lymphoma cell lines with CNTY-101 - - Company announces plans for Phase 1 ELiPSE-1 trial of CNTY-101 in relapsed/refractory lymphoma; IND submission on track for mid-2022 - - Data presented at ASH Annual Meeting support potential for γδ CAR-iT cells to deliver allogeneic T cell therapies without risk for GVHD; γδ cells chosen as initial focus of iT cell development program - - Company to host virtual research & development update today at 8:00 AM ET - PHILADELPHIA, Dec. 16, 2021 (GLOBE NEWSWIRE) -- Century Therapeutics (NASDAQ: IPSC), an innovative biotechnology company developing induced pluripotent stem cell (iPSC)-derived cell therapies in immuno-oncology, today announced updated preclinical data from the Company’s CNTY-101 program and CAR-iT platform. These data were presented during poster sessions at the recent 63rd American Society of Hematology (ASH) Annual Meeting & Exposition. Additionally, the Company provided pipeline program updates ahead of its virtual research & development update taking place today, December 16, at 8:00 AM ET. “Century continues to make rapid, measurable progress towards development of a next generation iPSC-based allogeneic cell therapy platform that features Allo-Evasion gene edits to potentially enable the benefit of multiple doses,” said Lalo Flores, Ph.D., Chief Executive Officer, Century Therapeutics. “Data presented at the ASH Annual Meeting add to the body of evidence supporting the differentiation hypothesis for our first iNK cell product, CNTY-101 and the decision to focus development of future iT cell candidates on our promising γδ iT cell platform. The commencement of the Phase 1 ELiPSE-1 trial, which will assess CNTY-101 in patients with relapsed/refractory aggressive lymphoma or indolent lymphoma, will be an important milestone for Century, and we look forward to potentially initiating the study by the end of 2022, subject to FDA acceptance of our IND application. Submission of the IND is planned for mid-2022.” “Developing a best-in-class iPSC derived T cell platform is a top priority at Century and we are excited to disclose promising data supporting our decision to prioritize our iPSC-derived γδ T cell platform for development of our first iT cell products,” said Luis Borges, Ph.D.,...

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