Press release
New Data at American College of Gastroenterology Annual Meeting Show TissueCypher® Provides Actionable Risk Insights that Influence Clinical Management and Prompt Risk-Aligned Intervention in Barrett’s Esophagus
Research on TissueCypher by Horvath et al. honored with a Presidential Poster Award from the ACG Abstract Selection Committee, a distinction awarded to only
About this update from Castle Biosciences, Inc.
[{"type":"text","content":"Research on TissueCypher by Horvath et al. honored with a Presidential Poster Award from the ACG Abstract Selection Committee, a distinction awarded to only 5-7% of abstracts for research deemed high quality, novel or unique\nFRIENDSWOOD, Texas, Oct. 26, 2025 (GLOBE NEWSWIRE) -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced new data demonstrating that its TissueCypher® Barrett’s Esophagus test can provide risk insights beyond pathology alone, influencing clinical management to support earlier intervention for those at higher risk of progression to esophageal cancer and potentially reducing unnecessary procedures for those at lower risk. The research will be presented in three posters at the American College of Gastroenterology (ACG) 2025 Annual Scientific Meeting, taking place Oct. 27–29, 2025, in Phoenix, Arizona, including one selected for a Presidential Poster Award. “Our findings being presented at ACG highlight how difficult it can be to accurately assess progression risk in patients with Barrett’s esophagus when relying on pathology alone,” said Edward Horvath, M.D., board-certified gastroenterologist at Gastro Health West Boynton in Boynton Beach, Florida. “By identifying patients at higher risk who may otherwise be missed, the TissueCypher test provides objective, individualized risk information that supports more personalized decisions around surveillance and intervention, helping clinicians act sooner to potentially reduce the risk of progression to esophageal cancer.” More than 6,400 scientific abstracts will be presented during ACG 2025. Only a small percentage of these received a Presidential Poster Award, recognizing high quality, novel, unique or interesting research, including the abstract by Horvath et al. highlighted below.* Two additional posters on TissueCypher will also be presented (all times Pacific Daylight Time). P0689: The Tissue Systems Pathology Test (TSP-9) Informs Management of Patients That Are Indefinite for Dysplasia to Predict Missed Prevalent Neoplasia Presenting Author: Ronen Arai, M.D., Gastro Health North Broward, Coral Springs, FloridaDate: Sunday, Oct. 26Time: 3:30-7:00 p.m.; author available to answer questions from 5:15-6:30 p.m.Summary: Pathologists may issue a finding of indefinite for dysplasia (IN...