Business
Caribou Biosciences Provides Business Update and Reports Third Quarter 2021 Financial Results
On track to achieve key milestones, including plan to disclose initial clinical data in 2022 for lead product candidate CB-010 Expanded leadership with
About this update from Caribou Biosciences, Inc.
[{"type":"text","content":"On track to achieve key milestones, including plan to disclose initial clinical data in 2022 for lead product candidate CB-010 Expanded leadership with appointments of Ran Zheng and Dara Richardson-Heron, M.D., to board of directors and Ruhi Khan as chief business officer Ended third quarter with strong cash position of $435.3 million BERKELEY, Calif., Nov. 09, 2021 (GLOBE NEWSWIRE) -- Caribou Biosciences, Inc. (Nasdaq: CRBU), a leading clinical-stage CRISPR genome-editing biopharmaceutical company, today reported business highlights and financial results for the third quarter of 2021. “Our important progress during 2021 continues as we advanced our lead therapeutic product candidate into the clinic, completed a successful IPO, and expanded our leadership team with highly experienced and regarded professionals,” said Rachel Haurwitz, Ph.D., Caribou’s president and chief executive officer. “Caribou’s differentiated chRDNA genome-editing technology and proprietary delivery approach enable high specificity multiplex editing, which we believe is key to the creation of sophisticated allogeneic CAR-T and CAR-NK therapies that have the potential to provide persistent antitumor activity. We are developing our four wholly-owned allogeneic cell therapy product candidates for the treatment of hematologic and solid tumors, including our lead product candidate, CB-010, which is being evaluated in the ANTLER Phase 1 clinical trial in patients with relapsed or refractory B cell non-Hodgkin lymphoma. We look forward to achieving key milestones in 2022, including our plans to disclose initial data from the ANTLER trial as well as to file an IND for our next product candidate, CB-011.” Recent Business Highlights Published data demonstrating the significantly improved specificity of Caribou’s proprietary CRISPR hybrid RNA-DNA (chRDNA) guide technology compared to all-RNA guides. In September 2021, Caribou and its collaborators published studies demonstrating that its CRISPR hybrid RNA-DNA (chRDNA) guide technology provides significantly improved specificity compared to all-RNA guides, thereby enabling high levels of intended genomic edits in cells while eliminating or minimizing inadvertent off-target events. Higher specificity is a key advantage of Caribou’s cell therapies and of critical importance in therapies that contain multiple genome edits...