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Cardio Diagnostics Holdings, Inc. Announces Breakthrough in Coronary Heart Disease Detection with PrecisionCHD Test, Published in the Journal of the American Heart Association
CHICAGO--(BUSINESS WIRE)-- Cardio Diagnostics Holdings, Inc. (Nasdaq: CDIO), a leader in artificial intelligence-driven precision cardiovascular medicine
About this update from Cardio Diagnostics Holdings Inc.
[{"type":"text","content":" CHICAGO--(BUSINESS WIRE)--\nCardio Diagnostics Holdings, Inc. (Nasdaq: CDIO), a leader in artificial intelligence-driven precision cardiovascular medicine tests, today announced the publication of its groundbreaking study in the Journal of the American Heart Association (JAHA), an official journal of the American Heart Association. This study, conducted in collaboration with Intermountain Healthcare and University of Iowa Hospitals and Clinics, describes the development and validation of PrecisionCHD, a pioneering artificial intelligence-guided integrated genetic-epigenetic test for detecting coronary heart disease (CHD).\n\n\nThe article entitled \"The Validation of an Integrated Genetic-Epigenetic Test for the Assessment of Coronary Heart Disease,\" unveils a significant leap in CHD diagnosis. Traditional diagnostic methods for CHD are often invasive, require exposure to ionizing radiation, and are not widely accessible due to the need for specialized infrastructure. Furthermore, some of the tests are not sensitive to all forms of CHD and can be very costly. As a result, millions of Americans do not receive adequate and potentially lifesaving cardiac care in a timely manner. With the introduction of PrecisionCHD, clinicians now have a powerful, scalable, non-invasive alternative, in the form of a blood-based test that uses artificial intelligence (AI) and personalized genetic and epigenetic information to sensitively detect the presence of CHD.\n\n\nThe study detailed in JAHA, conducted by researchers from Cardio Diagnostics, Intermountain Healthcare and the University of Iowa Hospitals and Clinics, describes the development and validation of the PrecisionCHD test in three independent cohorts totaling 2,516 individuals. PrecisionCHD is the first integrated genetic-epigenetic test for the detection of CHD that uses the input from six methylation sensitive digital PCR (MSdPCR) assessments to determine the presence or absence of CHD.\n\n\nThe article details the mapping of each of these MSdPCR assays to distinct modifiable drivers of CHD through which clinicians are able to gain personalized insights into each patient’s CHD presentation. In addition, the article notes that because methylation is dynamic, clinicians can consider focused re-testing to determine the effectiveness of CHD therapy. Robert Philibert MD Ph.D., lead auth...