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Cadrenal Therapeutics Recognizes National Kidney Month with Goal to Advance Tecarfarin for Severely Underserved Patient Population
Tecarfarin, a novel therapy designed for the prevention of systemic thromboembolism (blood clots) of cardiac origin in patients with End Stage Renal Disease
About this update from Cadrenal Therapeutics, Inc.
[{"type":"text","content":"Tecarfarin, a novel therapy designed for the prevention of systemic thromboembolism (blood clots) of cardiac origin in patients with End Stage Renal Disease and Atrial Fibrillation, may be a new treatment option for this underserved patient population\nPONTE VEDRA, Fla., March 9, 2023 /PRNewswire/ -- Cadrenal Therapeutics, Inc., (Nasdaq: CVKD) a biopharmaceutical company focused on developing tecarfarin, a clinical-stage novel cardiorenal therapy with orphan drug and Fast Track designations, recognizes National Kidney Month throughout the month of March as it advances tecarfarin for a severely underserved subset of the overall kidney disease population.\n\n \n \n \n \n \n \n\n \nOverall, Chronic Kidney Disease (CKD) affects almost 40 million American adults, with as many as 90% of Americans who have CKD not knowing they have the disease until it is very advanced. A more dire subset is the more than 800,000 Americans with End-Stage Renal Disease (ESRD), or permanent kidney failure that requires life-long dialysis or a kidney transplant. Nearly 20% of ESRD patients, or 150,000 individuals, also have Atrial Fibrillation (AFib) or an irregular heartbeat, which nearly doubles the anticipated mortality and increases the stroke risk by approximately five-fold in these patients. There is evidence that AFib is an independent risk factor for developing ESRD in CKD patients. Both diseases share common risk factors including hypertension, diabetes, vascular disease, and advancing age. Cardiovascular diseases contribute to more than half of all deaths among patients with ESRD.\nCadrenal is developing tecarfarin, a novel therapy which has been granted and orphan drug and Fast Track designations by the US FDA for the prevention of systemic thromboembolism (blood clots) of cardiac origin in patients with ESRD and AFib.\nAccording to the Annual Data Report published by the United States Renal Data System, total Medicare spending for patients with ESRD reached $51 billion in 2019, accounting for approximately 7% of the Medicare paid claims costs.\nQuang Pham, Founder and CEO of Cadrenal Therapeutics, commented, \"The presence of either chronic kidney disease or AFib increases the risk of serious thromboembolic adverse clinical outcomes, such as stroke and death. Antithrombotic therapy is typically recommended to decrease this risk in AFib patient...