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Bruker Launches Ultimate Sensitivity timsTOF Ultra 2 to Enable New Research Paradigms in Single-Cell and Subcellular Proteomics
timsTOF Ultra 2 enables significant further improvements in deep, high-fidelity 4D-Proteomics™ of mammalian cells, cancer cell lines, or tissue biopsies With
About this update from Bruker Corporation
[{"type":"text","content":"\n\ntimsTOF Ultra 2 enables significant further improvements in deep, high-fidelity 4D-Proteomics™ of mammalian cells, cancer cell lines, or tissue biopsies\n\n\n\nWith sensitivity to measure >1000 proteins on just 25 pg, the timsTOF Ultra 2 opens new cell and disease biology research windows into PBMCs, small immune cells, bacterial cells, or subcellular organelle proteomics\n\n\n\ntimsTOF Ultra 2 enables identification and quantitation of ~50% more protein groups and ~100% more peptides at 25 pg of digest sample with 1% FDR\n\n\n\ntimsTOF Ultra 2 typically yields ~40% more peptides and ~20% more proteins for many other 4D-Proteomics applications with low-medium sample amounts\n\n\n\nImproved ion-charge control (ICC 2.0) method makes timsTOF Ultra 2 suitable for a very broad range of sample loading, from low picograms to micrograms\n\n\n\nNew OmniScape™ top-down proteoform software for automated, near-complete protein sequence coverage from MALDI-ISD and LC-TIMS-MS/MS data\n\n\n\nBiognosys launches Spectronaut® 19 (SN19) with optimized AI for further increased depth of protein quantitation and greater peptide sequence coverage\n\n\n\nSN19 now specifically trained on timsTOF MS/MS for significant 4D-Proteomics performance improvements; SN19 now fully integrated into timsTOF Ultra 2\n\n\n\nPreOmics launches reproducible and affordable deep plasma 4D-Proteomics ENRICHplus kit for 7-fold plasma depth improvement on robust timsTOF HT\n\n\n\nNovel capabilities for 4D-glycoprotein analysis: glyco-PASEF® and GlycoScape™\n\n\n\nBruker announces customer shipment of more than 1,000 timsTOF systems\n\n\n\nBruker launches 3 mass spectrometers at ASMS 2024 for 4D-Proteomics, mass-spec multiomics tissue imaging, and for highest-confidence applied analysis\n\n\n\n ANAHEIM, Calif.--(BUSINESS WIRE)--\nAt the 72nd ASMS meeting, Bruker Corporation (Nasdaq: BRKR) launches the new top-of-the-line timsTOF Ultra 2 system with significantly further enhanced sensitivity for deep profiling of small cells, subcellular organelles, as well as increased sample loading flexibility. Together with new Spectronaut 19 software and the novel PreOmics ENRICHplus kit, Bruker is setting new 4D-Proteomics standards from highest sensitivity to large-scale, deep plasma proteomics. Bruker is also introducing OmniScape software for top-down sequence confirmation and de n...