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Bruker Advances CCS-Enabled 4D-Proteomics timsTOF Solutions for Immunopeptidomes and Glycoproteomics at US HUPO
Novor V2.0 software with novel ML algorithm trained on HLA peptides yields immunopeptidome from de novo peptide sequencing with further improved IDs
About this update from Bruker Corporation
[{"type":"text","content":"\n\nNovor V2.0 software with novel ML algorithm trained on HLA peptides yields immunopeptidome from de novo peptide sequencing with further improved IDs\n\n\n\nTwinScape™ digital-twin technology with iRT™ standards supports highest timsTOF performance with intelligent feedback – well beyond ‘just up-time’\n\n\n\nNew glyco-PASEF® method for ultra-high sensitivity 4D glycopeptide analysis\n\n\n\nSpectronaut® 18 software now available for Bruker ProteoScape™ users\n\n\n\nBiognosys launches high-throughput ENRICHMENT plasma proteomics service for large-scale quantification of ~4.5k proteins with ~55k peptides at 1% FDR specificity\n\n\n\nPreOmics® sample prep tools for proteomics now with >50 BeatBox® placements for fast cell lysis and affordable, high-performance FFPE/FF tissue homogenization\n\n\n\n PORTLAND, Ore.--(BUSINESS WIRE)--\nAt the 20th US Human Proteome Organization Congress 2024, Bruker Corporation (Nasdaq: BRKR) announced progress in immunopeptidomics, glycoproteomics and other CCS-enabled 4D-proteomics workflows. The rapid advances in deep, at-scale proteomics, glycomics and peptidomics research solutions complement other performance-leading life-science tools for the post-genomic era by Bruker. Together they enable post-genomic molecular and cell biology research, with key insights into disease biology and biomarkers for next-gen molecular diagnostics and drug discovery.\n\nThis press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20240311088724/en/Bruker's Immunopeptidomics Workflow (Graphic: Business Wire)\nThe advances featured at US HUPO include improved machine-learning de novo sequencing (Novor V2.0), a novel high-performance monitoring digital-twin software (TwinScape), the new glyco-PASEF method for high-sensitivity glycopeptide analysis, and access to Spectronaut 18 for users of Bruker ProteoScape, a GPU-powered software for real-time 4D proteomics, now with access to library-free searches by Biognosys directDIA®.\n\n\nA. Advancing Cancer Immunotherapy Research\n\n\nBruker enhances its timsTOF HT and timsTOF Ultra systems with the new software Novor v2.0 for de novo immunopeptidomic profiling. Novor v2.0, developed in collaboration with Rapid Novor Inc., was trained on >1,400,000 spectra mapping to >150,000 HLA peptides for research on small amounts of patient...