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BridgeBio Pharma to Present Updated Results from Phase 2 Open-label Extension Study of Acoramidis in Transthyretin Amyloid Cardiomyopathy (ATTR-CM) at the American College of Cardiology (ACC) Annual Scientific Session & Expo
PALO ALTO, Calif., March 28, 2022 (GLOBE NEWSWIRE) -- BridgeBio Pharma, Inc. (Nasdaq: BBIO) (“BridgeBio” or the “Company”), a commercial-stage
About this update from Bridgebio Pharma, Inc.
[{"type":"text","content":"PALO ALTO, Calif., March 28, 2022 (GLOBE NEWSWIRE) -- BridgeBio Pharma, Inc. (Nasdaq: BBIO) (“BridgeBio” or the “Company”), a commercial-stage biopharmaceutical company focused on genetic diseases and cancers, today announced that updated data from its ongoing Phase 2 open-label extension (OLE) study of acoramidis (AG10) in patients with symptomatic transthyretin (TTR) amyloid cardiomyopathy (ATTR-CM) will be featured in an oral presentation at the American College of Cardiology (ACC) Annual Scientific Session & Expo, taking place in Washington, D.C. on April 2 – 4, 2022. Additionally at ACC 2022, BridgeBio will share an analysis on the unmet needs in care and quality of life for patients with ATTR to support the Company’s ongoing research to better serve the patient community. Full oral presentation and poster details are listed below. BridgeBio’s Phase 3 study investigating acoramidis in ATTR-CM (ATTRibute-CM) is ongoing with topline data expected in mid-2023 on the Month 30 primary endpoint, which is a hierarchical composite including all-cause mortality and cardiovascular hospitalizations. BridgeBio Oral Presentation & Poster Details:Long-term Safety and Tolerability of Acoramidis (AG10) in Symptomatic Transthyretin Amyloid Cardiomyopathy: Updated Analysis from an Ongoing Phase 2 Open-label Extension StudyPresenter: Ahmad Masri, M.D. MS, director of the cardiac amyloidosis program at Oregon Health & Science UniversityDate/ Time: April 3, 2022, 8:36 AM - 8:46 AMLocation: Room 204ASession & Abstract Number: Session 903, Highlighted Original Research: Heart Failure and Cardiomyopathies and the Year in Review; Abstract #903-08 Unmet Needs Among Patients with Transthyretin Amyloidosis (ATTR) and Call for Additional ResearchDate/ Time: April 2, 2022, 3:45 PM - 4:30 PMLocation: Poster Hall CSession & Abstract Number: Session 1364 - Heart Failure and Cardiomyopathies: Population Science 6, Abstract #1364-135 About AcoramidisAcoramidis (AG10) is an investigational, orally-administered small molecule designed to potently stabilize tetrameric transthyretin, or TTR, thereby halting at its outset the series of molecular events that give rise to TTR amyloidosis, or ATTR. Acoramidis is currently being evaluated in Phase 2 and Phase 3 studies in patients with ATTR. Acoramidis was designed to mimic a naturally-occurring variant of the TTR ge...