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BioRestorative Therapies Enters Agreement with Regenexx, Granting BRTX Exclusive License Rights for Intellectual Property Related to the Development and Commercialization of its BRTX-100® Disc Program to Treat Chronic Lumbar Disc Disease
-- Intellectual Property Provides a Cell-Based Therapeutic Platform Designed to Target All Avascular Zones-- MELVILLE, N.Y., Dec. 05, 2022 (GLOBE NEWSWIRE) --
About this update from Biorestorative Therapies, Inc.
[{"type":"text","content":"-- Intellectual Property Provides a Cell-Based Therapeutic Platform Designed to Target All Avascular Zones-- MELVILLE, N.Y., Dec. 05, 2022 (GLOBE NEWSWIRE) -- BioRestorative Therapies, Inc. (“BioRestorative” or the “Company”) (NASDAQ: BRTX), a clinical stage company focused on stem cell-based therapies, today announced an agreement with Regenexx, LLC pursuant to which the license rights granted by Regenexx to the Company for intellectual property developed to address chronic lumbar disc disease have been made exclusive. The intellectual property now exclusively licensed to the Company represents important technological framework for BRTX’s disc/spine technology related to the Company’s BRTX-100® lead clinical program, currently in a Phase 2 trial with approximately 15 sites selected across the United States. The intellectual property was developed in the lab of Dr. Christopher Centeno. Dr. Centeno has been a leader in the field of cellular therapy for musculoskeletal indications for over 17 years. “This is an important event for BioRestorative. We are thrilled to now have through this agreement an exclusive license with regard to Regenexx’s technology,” said Lance Alstodt, Chief Executive Officer at BioRestorative. “With this agreement, coupled with our unique in-house research and manufacturing capabilities, we aim to create a new generation of cell-based products to induce long-term and sustained pain relief for patients suffering from musculoskeletal indications. Approximately $40 billion is spent annually on invasive surgical procedures. With BRTX-100, the Company is seeking to provide a paradigm shifting, non-invasive solution to millions of patients worldwide.” The BRTX-100 platform is a cell-based technology that utilizes low oxygen (hypoxia) to engineer the cells’ modulation strategy to repress or activate transcription of target genes related to tissue remodeling. Data from early investigator-initiated human studies suggest a potential for this platform to regulate target hypoxia-dependent gene expression as a means to improve upon both the efficacy and safety of first-generation cell-based therapies. “Regenexx is excited to have granted exclusive license rights to BioRestorative and support their efforts as they continue to develop the technology through the regulatory pathway. We have a great deal of clinical experien...