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Bionano Genomics Releases Saphyr Updates for Industry-Leading Data Yields that Enable Analysis of Complex Cancer Samples at Unprecedented Depths
Bionano now offering genome analysis services and reagent rental options making it easier than ever for scientists and clinicians to get Bionano Data SAN
About this update from Bionano Genomics, Inc.
[{"type":"text","content":"Bionano now offering genome analysis services and reagent rental options making it easier than ever for scientists and clinicians to get Bionano Data\nSAN DIEGO, Feb. 24, 2020 (GLOBE NEWSWIRE) -- Bionano Genomics (NASDAQ: BNGO) today announced updates to the Saphyr® System designed to increase the speed of data collection, simplify sample preparation for solid tumors and animal tissue and significantly improve the total data yield per flow cell, allowing for a complete workflow for the in-depth analysis of complex, heterogeneous cancer samples. Bionano is also introducing two new ways for customers to access Bionano data: the first, by offering a competitively priced service for human genome analysis, and the second, a reagent-rental model that provide scientists and labs with the Saphyr system when they make a certain minimum commitment to purchase Bionano consumables.\n As a result of the updates announced today, Saphyr can collect as much as 5 Terabasepairs of data, or over 1500x coverage of a human genome, in 48 to 96 hours on three samples in parallel, for a total of 15 Tbp on a single Saphyr Chip. Improvements to the Saphyr System’s control software have continued to increase the throughput of the instrument, allowing for the analysis of 9 human genomes per 24 hours at 100x coverage of a human genome, or 3 human genomes per 24 hours at 400x coverage on the second generation Saphyr. With the per-genome cost starting at $450 for Saphyr owners, the cost of Bionano data can be $0.09 per Gigabasepair. This unprecedented amount of genomic data allows the Bionano Solve pipeline to detect all major structural variant types genome wide, unbiased, with sensitivities over 90% down to 1% variant allele fraction, which in turn enables the comprehensive analysis of structural variants in small subclones of heterogeneous cancer samples, or the detection of rare variants occurring during genome modification, such as off-target effects of CRISPR-based gene editing. As with previous throughput increases, Bionano is enabling this capability for all existing customer inventory of second generation Saphyr Chips to speed novel discoveries. The scope of supported sample types with the Bionano Prep SP kit will be expanded to include human and animal tissues. The Bionano Prep SP kit now enables easy and fast extraction of ultra-high molecular weig...