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ScaleReady awards multiple G-Rex® Grants to leading investigators at the University of Southern California (USC) and the Children's Hospital of Los Angeles (CHLA)
ST. PAUL, Minn., May 14, 2025 /PRNewswire/ -- ScaleReady, in collaboration with Wilson Wolf Manufacturing, Bio-Techne Corporation (NASDAQ: TECH) and CellReady
About this update from Bio-techne Corp
[{"type":"text","content":"ST. PAUL, Minn., May 14, 2025 /PRNewswire/ -- ScaleReady, in collaboration with Wilson Wolf Manufacturing, Bio-Techne Corporation (NASDAQ: TECH) and CellReady announced today three G-Rex Grants that have been awarded to faculty members at the University of Southern California (USC) and the Children's Hospital of Los Angeles (CHLA). The funding totaling $1,025,000 will support the translation of various cell and gene therapy initiatives into the clinic.\nDr. Mohamed Abou-el-Enein, Executive Director of the USC/CHLA Cell Therapy Program and Founding Director of the cGMP Facility, received a $300,000 G-Rex Grant to further support the development of a novel non-viral manufacturing platform for CAR-T cell therapies. Initially funded by the INFR5 Grant from the California Institute of Regenerative Medicine (CIRM), this additional support will help accelerate and enhance the platform's progress.\n\"After extensive evaluation, we've identified the G-Rex system as the platform of choice for establishing an efficient, scalable, and cost-effective CAR-T manufacturing process that supports both my lab and our clients within the GMP facility. The system enables high-yield cell expansion, robust scale-up, and impressive consistency within a compact footprint. By integrating this platform, we are advancing our mission as a center of excellence in CAR-T manufacturing and delivering practical solutions for teams bringing cell therapies to patients,\" said Mohamed Abou-el-Enein M.D., Ph.D.\nDr. Saul Priceman, Founding Director of the Keck School of Medicine of USC/ USC Norris Comprehensive Cancer Center for Cancer Cellular Immunotherapy Research (CCCIR), received a $275,000 G-Rex Grant for the development of a G-Rex based CAR-T cell process to advance a novel clinically-active CAR-T cell therapy into a Phase 1/2 clinical trial for the treatment of metastatic solid cancers. The laboratory is also investigating viral and non-viral engineering strategies that will be adapted using the G-Rex platform, which will address current cell manufacturing bottlenecks and help expand preclinical and clinical research efforts. \"While our clinical experiences to date have used more conventional cell manufacturing platforms, we are excited about translating our new cellular immunotherapies using the G-Rex production system across the USC and CHLA campuses,\" sa...