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Axon Therapies Raises $32M in Oversubscribed Series A to Transform Heart Failure Treatment

Axon Therapies, a clinical-stage medical device company pioneering a new approach to treating heart failure, today announced the close of an oversubscribed $32 million Series A financing. The round was co-led by new investors Earlybird Venture Capital and Santé Ventures, with participation by existing investor Deerfield Management and new investors CD Capital and KOFA Healthcare.

articleAxon Enterprise, Inc.September 25, 20253/company/axon-enterprise-inc/news/axon-therapies-raises-dollar32m-in-oversubscribed-series-a-to-transform-heart-failure-treatment
Axon Therapies Raises $32M in Oversubscribed Series A to Transform Heart Failure Treatment

About this update from Axon Enterprise, Inc.

[{"type":"text","content":"Funding supports clinical trials of a minimally invasive therapy targeting a root cause of heart failure; co-founder Zoar Engelman, PhD, appointed CEO","length":150,"tagName":"p"},{"type":"text","content":"NEW YORK, Sept. 25, 2025 /PRNewswire/ -- Axon Therapies, a clinical-stage medical device company pioneering a new approach to treating heart failure, today announced the close of an oversubscribed $32 million Series A financing. The round was co-led by new investors Earlybird Venture Capital and Santé Ventures, with participation by existing investor Deerfield Management and new investors CD Capital and KOFA Healthcare.","length":423,"tagName":"p"},{"type":"image","alt":"Co-founder Zoar Engelman, PhD, appointed CEO of Axon Therapies","displaySize":"","headline":null,"caption":"Co-founder Zoar Engelman, PhD, appointed CEO of Axon Therapies","className":"","disableSlideshowImg":false,"size":{"original":{"width":302,"height":400,"url":"https://media.zenfs.com/en/prnewswire.com/086d66c51785f37ffad3f90fb8ccc3ec"},"resized":{"url":"https://s.yimg.com/ny/api/res/1.2/A4f2F4Ppk7hsN9fhI6RRnw--/YXBwaWQ9aGlnaGxhbmRlcjt3PTQyMDtoPTU1NjtjZj13ZWJw/https://media.zenfs.com/en/prnewswire.com/086d66c51785f37ffad3f90fb8ccc3ec","width":302,"height":400}},"href":"https://mma.prnewswire.com/media/2782398/Axon_Zoar_Engelman.html","hrefExternal":true,"rel":"nofollow"},{"type":"text","content":"The financing will accelerate Axon's next phase of clinical development, including two double-blinded randomized feasibility studies in heart failure – a condition that affects millions of people worldwide with limited treatment options. The first is a confirmatory study for its novel splanchnic ablation therapy in patients with Heart Failure with Preserved Ejection Fraction (HFpEF). The second is a multiple-center study of splanchnic ablation in Failure with Reduced Ejection Fraction (HFrEF).","length":502,"tagName":"p"},{"type":"text","content":"In conjunction with the financing, the company announced that Zoar Engelman, PhD, Axon's co-founder and former Chief Scientific Officer, has been appointed Chief Executive Officer.","length":184,"tagName":"p"},{"type":"text","content":""Heart failure is one of the leading causes of hospitalization and death worldwide, yet patients still face a lack of effective treatment options," said Dr. Engelman, CE...

More updates from Axon Enterprise, Inc.

Zoar Engelmanheart failureDeerfield ManagementDr. Engelmanminimally invasive therapyVenture Capitaltreatment optionsAxonCD Capitalpatientsclinical trials