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Atea Pharmaceuticals Presents New Drug-Drug Interaction Results Supporting Potential Best-in-Class Profile of the Regimen of Bemnifosbuvir and Ruzasvir for the Treatment of Hepatitis C Virus at EASL Congress 2026
Atea Pharmaceuticals Presents New Drug-Drug Interaction Results Supporting Potential Best-in-Class Profile of the Regimen of Bemnifosbuvir and Ruzasvir for the Treatment of Hepatitis C Virus at EASL Congress 2026
About this update from Atea Pharmaceuticals, Inc.
[{"type":"text","content":"Additional Data Presented Demonstrate High In Vitro Antiviral Potency and In Vivo Efficacy for AT-587, Atea’s Potential First-in-Class Direct-Acting Antiviral for the Treatment of Hepatitis E Virus\nBOSTON, May 27, 2026 (GLOBE NEWSWIRE) -- Atea Pharmaceuticals, Inc. (Nasdaq: AVIR) (Atea or Company), a late-stage clinical biopharmaceutical company engaged in the discovery and development of oral antiviral therapeutics for serious viral diseases, today announced Phase 1 results which further demonstrate that the fixed-dose combination regimen of bemnifosbuvir and ruzasvir (BEM/RZR) for the treatment of hepatitis C virus (HCV) has a low risk of drug-drug interaction. These results support the use of BEM/RZR with commonly used medications, including the proton pump inhibitor (PPI) omeprazole and the cholesterol-lowering drug rosuvastatin. The Company is also presenting data demonstrating high in vitro antiviral potency and in vivo efficacy for AT-587, its potential first-in-class direct-acting antiviral (DAA) for the treatment of hepatitis E virus (HEV). These data are being presented at the European Association for the Study of the Liver (EASL) Congress 2026, taking place May 27-30th in Barcelona, Spain. “These Phase 1 results reinforce the potential of the regimen of BEM/RZR to simplify treatment for patients and healthcare providers and address the evolving needs of today’s patients living with HCV,” said Jean-Pierre Sommadossi, PhD, Chief Executive Officer and Founder of Atea Pharmaceuticals. “Our market research has shown that most HCV patients in the US manage multiple medications concurrently, which can complicate care. The results being presented demonstrate that the regimen of BEM/RZR can be co-administered with PPIs and other commonly used medications without requiring dose adjustments. As we move toward topline Phase 3 results from C-BEYOND and C-FORWARD, these data give us continued confidence in the regimen's potential to deliver a best-in-class profile for today’s patients living with HCV.” HCV continues to be a significant global health burden despite the availability of DAAs. According to US healthcare providers who treat patients with HCV, approximately 80 percent of patients take multiple medications to manage comorbidities and drug-drug interactions are a significant concern in HCV treatment. As a result, a new tr...