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Atea Pharmaceuticals Presents Multiple New Datasets Supporting the Combination of Bemnifosbuvir and Ruzasvir for the Treatment of Hepatitis C Virus at AASLD’s The Liver Meeting 2024
BOSTON, Nov. 15, 2024 (GLOBE NEWSWIRE) -- Atea Pharmaceuticals, Inc. (Nasdaq: AVIR) (“Atea”), a clinical-stage biopharmaceutical company engaged in the
About this update from Atea Pharmaceuticals, Inc.
[{"type":"text","content":"BOSTON, Nov. 15, 2024 (GLOBE NEWSWIRE) -- Atea Pharmaceuticals, Inc. (Nasdaq: AVIR) (“Atea”), a clinical-stage biopharmaceutical company engaged in the discovery and development of oral antiviral therapeutics for serious viral diseases, today presented three poster presentations supporting the combination of bemnifosbuvir and ruzasvir as a potential treatment for hepatitis C virus (HCV). The combination of bemnifosbuvir, a nucleotide analog polymerase inhibitor, and ruzasvir, an NS5A inhibitor, is in Phase 2 development for the treatment of HCV. These data are being presented at the American Association for the Study of Liver Diseases’ (AASLD) The Liver Meeting 2024, being held from November 15-19, 2024 in San Diego, CA. “These important data presented today at The Liver Meeting add to the growing body of evidence supporting the combination of bemnifosbuvir and ruzasvir and its potential best-in-class profile for the treatment of HCV,” said Jean-Pierre Sommadossi, PhD, Chief Executive Officer and Founder of Atea Pharmaceuticals. “We expect to report results from our Phase 2 study of the combination of bemnifosbuvir and ruzasvir in early December and we look forward to initiating Phase 3 development in early 2025. Our combination includes the most compelling attributes of current HCV drug treatments such as convenience, low risk for drug-drug interactions, as well as short duration, which is further supported by the viral kinetic modeling results presented today. We believe our combination has the potential to address current treatment challenges and unmet needs and to play a major role in the eradication of HCV.” “A multiscale model of HCV infection and treatment was designed to estimate the in vivo effectiveness of agents including various combinations of direct-acting antivirals to block HCV replication and viral assembly,” said Alan Perelson, PhD, Senior Fellow at Los Alamos National Laboratory. “The data presented today modeling the combination of bemnifosbuvir and ruzasvir for the treatment of HCV align with the reported clinical results from the lead-in cohort of the Phase 2 study. These data are highly encouraging and show a SVR12 rate of 97% and support a short eight-week course of treatment.” Poster Number: 1467Date and Time: Friday, November 15, 1:00 p.m. – 2:00 p.m. PTLocation: San Diego Convention CenterTitle: Multis...