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ASH 2025 | Ascentage Pharma Presents Encouraging Data from Phase Ib/II Study of Bcl-2 Inhibitor Lisaftoclax in Venetoclax–Exposed Patients with Myeloid Malignances

Preliminary clinical evidence of Lisaftoclax overcoming venetoclax resistance in myeloid malignancies with a 31.8% overall response rate(ORR) in this subgroup of patients80% ORR achieved in newly diagnosed high-risk MDS/CMMLStrong safety profile with no dose-limiting toxicities across all patient cohorts in 103-patient study ROCKVILLE, Md. and SUZHOU, China, Dec. 07, 2025 (GLOBE NEWSWIRE) -- Ascentage Pharma Group International (NASDAQ: AAPG; HKEX: 6855), a global, commercial stage, integrated b

articleAscentage Pharma Group InternationalDecember 7, 20259/company/ascentage-pharma-grp-international/news/ash-2025-or-ascentage-pharma-presents-encouraging-data-from-phase-ibii-study-of-bcl-2-inhibitor-lisaftoclax-in-venetoclax-exposed-patients-with-myeloid-malignances
ASH 2025 | Ascentage Pharma Presents Encouraging Data from Phase Ib/II Study of Bcl-2 Inhibitor Lisaftoclax in Venetoclax–Exposed Patients with Myeloid Malignances

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Ascentage Pharma Group InternationalAscentage PharmaAZAacute myeloid leukemiaThe Companypatients with chronicmalignanciesstudyAmerican Society of Hematology