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Artelo Biosciences Announces Publication of New Peer-Reviewed Research Demonstrating Protective Properties of ART27.13 Against Muscle Degeneration Caused by Certain Cancers
SOLANA BEACH, Calif., Nov. 09, 2023 (GLOBE NEWSWIRE) -- Artelo Biosciences, Inc. (Nasdaq: ARTL), a clinical-stage pharmaceutical company focused on modulating
About this update from Artelo Biosciences, Inc.
[{"type":"text","content":"SOLANA BEACH, Calif., Nov. 09, 2023 (GLOBE NEWSWIRE) -- Artelo Biosciences, Inc. (Nasdaq: ARTL), a clinical-stage pharmaceutical company focused on modulating lipid-signaling pathways to develop treatments for people living with cancer, pain, and neurological conditions, today announced new research published in the peer-reviewed journal Pharmaceuticals. The research article, titled “Cancer-Cachexia-Induced Human Skeletal Muscle Myotube Degeneration is Prevented via Cannabinoid Receptor 2 Agonism in Vitro,” highlights the promising protective properties of the Company’s clinical asset, ART27.13, in helping prevent muscle degeneration caused by cancer. Senior author Dr. Richard K. Porter, Associate Professor at Trinity College Dublin, Ireland, stated, “This groundbreaking research demonstrated ART27.13’s ability to protect against muscle degeneration associated with colon and lung cancers. Based on this in vitro data, ART27.13 has the potential to protect against muscle wasting, which could result in increased quality of life and may ultimately impact life expectancy for patients suffering from cancer.” Artelo is currently evaluating ART27.13, a dual CB1/CB2 receptor agonist, in the Cancer Appetite Recovery Study (CAReS) Phase 2a clinical trial to determine its effect on lean body mass, weight gain, activity levels, and improvement of anorexia in cancer patients. The purpose of this new research was to establish whether ART27.13 may additionally impact muscle degradation, a common debilitating effect of cancer and its treatment. Not only did the research show that ART27.13 protects against muscle wasting in the in vitro model, but also shows that the activity was mediated by the CB2 receptor. Steven D. Reich, M.D., Chief Medical Officer of Artelo, commented “This in vitro data supports our confidence in ART27.13’s potential as a supportive care therapy for cancer patients as it may not only increase appetite, but also prevent muscle wasting. We are actively enrolling patients in the trial and look forward to reporting on our continued progress.” Professor Richard K. Porter authored the research paper in collaboration with Professor Saoirse O’Sullivan, Vice President of Translational Sciences at Artelo, Dr. Andrew Yates, Senior Vice President and Chief Scientific Officer of Artelo, together with Dr. John Noone, Dr. Mary F. Rooney ...