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Artelo Biosciences Announces Important New Data on ART26.12 Demonstrating Positive Effects in Multiple Models of Neuropathic Pain at the 33rd Annual International Cannabinoid Research Society Symposium
ART26.12, a Novel Fatty Acid Binding Protein 5 (FABP5) Inhibitor, Shows Favorable Results in Studies for Chemotherapy-Induced Neuropathy and Diabetic
About this update from Artelo Biosciences, Inc.
[{"type":"text","content":"ART26.12, a Novel Fatty Acid Binding Protein 5 (FABP5) Inhibitor, Shows Favorable Results in Studies for Chemotherapy-Induced Neuropathy and Diabetic Neuropathy ART26.12 targeting global neuropathic pain market valued at $7.6 billion in 2023 Anticipates FDA pre-IND meeting minutes during the third quarter of 2023 SOLANA BEACH, Calif., June 27, 2023 (GLOBE NEWSWIRE) -- Artelo Biosciences, Inc. (Nasdaq: ARTL), a clinical-stage pharmaceutical company focused on modulating lipid-signaling pathways to develop treatments for people living with cancer, pain, and neurological conditions, announced that Professor Saoirse O’Sullivan, Vice President of Translational Sciences at Artelo, presented preclinical data related to ART26.12, Artelo’s novel fatty acid binding protein 5 (FABP5) inhibitor at the 33rd International Cannabinoid Research Society (ICRS) Symposium in Toronto, Ontario, Canada. “Growing evidence of ART26.12’s activity on neuropathic pain caused by various chemotherapies or diabetes further substantiates developing our potent and novel FABP5 inhibitor as an innovative new treatment for painful neuropathies,” said Gregory D. Gorgas, Artelo’s President and Chief Executive Officer. There are very limited therapeutic options currently available and these existing treatments are often associated with a significant and undesirable side effect profile. According to Coherent Market Insights, the global neuropathic pain market is estimated to be valued at $7.6 billion. “We are making substantial progress in advancing this important program towards the clinic and are looking forward to receiving pre-IND meeting minutes from the FDA during the third quarter of this year, which will mark a substantial milestone for ART26.12,” added Mr. Gorgas. “ART26.12 continues to demonstrate a positive effect in numerous animal models of painful neuropathies, specifically chemotherapy-induced peripheral neuropathy (CIPN) and diabetic neuropathy,” said Professor O’Sullivan. “We were pleased to present new data with paclitaxel that confirms a previous study with oxaliplatin-induced CIPN which suggests a common mechanism of action of ART26.12 that is capable of preventing allodynia from both taxane- and platinum-based agents, the two most common causes of CIPN,” continued Professor O’Sullivan “In another animal study, orally administered ART26.12 demonst...