Press release
Arcturus Therapeutics Joint Venture mRNA Manufacturing Partner, ARCALIS, Awarded Additional Financial Grants from Japanese Government
$165 million in manufacturing grants awarded to ARCALIS by the Japanese government SAN DIEGO--(BUSINESS WIRE)-- Arcturus Therapeutics Holdings Inc. (the
About this update from Arcturus Therapeutics Holdings Inc.
[{"type":"text","content":"\n$165 million in manufacturing grants awarded to ARCALIS by the Japanese government\n\n\n SAN DIEGO--(BUSINESS WIRE)--\nArcturus Therapeutics Holdings Inc. (the “Company”, “Arcturus”, Nasdaq: ARCT), a global late-stage clinical messenger RNA medicines company focused on the development of infectious disease vaccines and opportunities within liver and respiratory rare diseases, announced today that ARCALIS, Arcturus’ manufacturing joint venture in Japan to support the production of mRNA vaccines and therapeutics, has been selected by the Japanese Ministry of Economy, Trade and Industry to receive additional financial support to construct a DNA template manufacturing facility along with new state-of-the-art equipment. In total to date, $165 million has been awarded to ARCALIS by the Japanese government to build mRNA Drug Substance, mRNA Drug Product manufacturing capabilities and to construct a DNA template manufacturing facility. The mRNA Drug Substance manufacturing facility was completed in July 2023.\n\n\nARCALIS will provide cGMP-integrated vaccine manufacturing, from mRNA drug substance to bulk nanoparticle-formulated drug product. This new capital will fund the development of a DNA plasmid production process to support the rapid manufacture of various vaccines and therapeutics, investigational drugs, and mRNA-based medicines. The new facility is designed to accelerate vaccine production by enabling the manufacturing of DNA plasmid and delivering vaccines within 100 days of the declaration of a target viral strain. The DNA plasmid generated at this facility is intended to be used as the key starting material in the manufacture of mRNA Drug Substance at the neighboring facility.\n\n\n“We are grateful for the deep commitment and generous financial support provided by the Japanese government to develop and manufacture next-generation mRNA-based vaccines,” said Joseph Payne, President & Chief Executive Officer of Arcturus Therapeutics. “This support has already enabled the completion of a state-of-the-art mRNA Drug Substance manufacturing facility, and we are excited to now extend this collaboration with the construction of an associated DNA manufacturing facility. These facilities, along with additional equipment and manufacturing capabilities, will allow ARCALIS to be leaders in the production of effective novel vaccines and ...