Business
Aptamer & Neuro-Bio to develop Alzheimer’s test
Aptamer & Neuro-Bio to develop Alzheimer’s test.
About this update from Aptamer Group Plc
[{"type":"text","content":"\n\n14 June 2023\n \nAptamer Group plc\n(\"Aptamer\", or \" the Group\")\n \nAptamer Group and Neuro-Bio partner to develop an Alzheimer's disease diagnostic test\n \n- Optimer binders have been successfully developed to a novel Alzheimer's disease biomarker\n- Aptamer Group CTO, Dr David Bunka, will present at Neuro-Bio's Science Day on Optimer technology and the development of binders to support the diagnostic\nAptamer Group plc (AIM: APTA), the developer of novel Optimer® binders to enable innovation in the life sciences industry, and Neuro-Bio, an Oxford-based biotechnology company with a therapeutic focus on neurodegenerative disease, announce success in the development of Optimer binders to enable a lateral flow test for the early diagnosis of Alzheimer's disease.\nAptamer Group has successfully developed a panel of Optimer binders to a novel Alzheimer's disease biomarker. The Optimer binders have been patented by partners at Neuro-Bio, following the demonstration of performance in specifically binding to the target biomarker and functionality in a nasal mucous matrix. Further integration of the binders into a routine lateral flow test will support the clinical and commercial development of rapid diagnostics for Alzheimer's disease via simple nasal sampling, with the potential to diagnose the disease as early as 10-20 years before symptoms emerge.\nThe novel Alzheimer's disease biomarker, a peptide 'T14'was discovered and is currently being further validated by Neuro-Bio, led by the eminent neuroscientist Baroness Susan Greenfield. Early detection of Alzheimer's disease is critical to allow interventions that could prevent the onset of devastating memory loss and confusion in these patients. Neuro-Bio is working in parallel to develop a complementary therapy that could stabilise disease progression in diagnosed patients, ideally at the presymptomatic stage.\nDr David Bunka, Chief Technical Officer of Aptamer Group, will take part in Neuro-Bio's Science Day today at the Royal College of Physicians, discussing the development of the Optimer binders in partnership with Neuro-Bio, and the potential for diagnostic development.\nDr Rob Quinn, Interim Chief Executive Officer of Aptamer Group, commented: \"We are pleased...