Business
Appili Therapeutics Announces Submission of U.S. Federal Government Funding Proposals and Provides Corporate and Aditxt Transaction Update
Four new funding proposals, totalling US$117.5 million, have been submitted for review Modi...
About this update from Appili Therapeutics Inc Class A
[{"type":"text","content":"Appili Therapeutics Announces Submission of U.S. Federal Government Funding Proposals and Provides Corporate and Aditxt Transaction Update\n\n\n\n\n Four new funding proposals, totalling US$117.5 million, have been submitted for review\n \n\n\n Modifications received to U.S. Air Force Academy Cooperative Agreement\n \n\n\n Outside date for going-private transaction extended to March 31, 2025\n \n\n\n HALIFAX, Nova Scotia, March 18, 2025 (GLOBE NEWSWIRE) -- Appili Therapeutics Inc. (TSX: APLI; OTCPink: APLIF) (the “Company” or “Appili”), a biopharmaceutical company focused on drug development for infectious diseases and medical countermeasures, today announced that, the Company along with its partners, have submitted applications for four new federal funding opportunities. The funding, if awarded, would total up to US$117.5 million and support the company’s efforts to advance urgent infectious disease treatments aligned with critical public health priorities.\n \n\n\n Funding Opportunities\n \n\n\n By leveraging Appili’s proven government contracting expertise, the Company and its partner have applied for two solicitations announced by the National Institute of Allergy and Infectious Diseases (“NIAID”). The first proposal seeks US$46.3 million in funding to develop a vaccine aimed at protecting against invasive fungal infections. The second proposal requests US$36.4 million to develop an antifungal monoclonal antibody targeting a rare fungal infection. If awarded, the NIAID funds are expected to support development of both products through to Investigational New Drug (“IND”) applications and Phase 1 clinical studies.\n \n\n Appili also submitted two proposals to the US Medical CBRN Defense Consortium (“MCDC”) seeking a total of US$34.8 million. The first proposal seeks US$20.1 million to develop a potential broad-spectrum host-directed treatment for viral infections. This project, developed in collaboration with partners, aims to address the critical medical needs for warfighters at high risk of exposure to dangerous viral infections. The second proposal submitted to MCDC, seeks US$14.7 million to develop a broad-spectrum direct-acting antiviral, potentially useful for treating patients infected with RNA viruses such as influenza, coronavirus, Wes...