Press release
Anavex Life Sciences Announces Notice of Allowance for U.S. Patent Application with Expanding Claims Covering ANAVEX®2-73 (blarcamesine) for the Treatment of Rett Syndrome and other Neurodevelopmental Disorders
Issuance of Its Newest U.S. Patent Will Strengthen Anavex’s Compounds Intellectual Property Portfolio NEW YORK, Nov. 30, 2020 (GLOBE NEWSWIRE) -- Anavex Life
About this update from Anavex Life Sciences Corp.
[{"type":"text","content":"Issuance of Its Newest U.S. Patent Will Strengthen Anavex’s Compounds Intellectual Property Portfolio\nNEW YORK, Nov. 30, 2020 (GLOBE NEWSWIRE) -- Anavex Life Sciences Corp. (“Anavex” or the “Company”) (Nasdaq: AVXL), a clinical-stage biopharmaceutical company developing differentiated therapeutics for the treatment of neurodegenerative and neurodevelopmental disorders including Alzheimer’s disease, Parkinson’s disease, Rett syndrome and other central nervous system (CNS) disorders, today announced it received a Notice of Allowance from the United States Patent and Trademark Office (USPTO) for its patent application number 16/717,921 expanding coverage of treatment methods for ANAVEX®2-73 (blarcamesine) and related sigma-1 receptor agonist drug candidates, for treating a range neurodevelopmental disorders including Rett syndrome, autism spectrum disorder, Angelman syndrome, cerebral palsy and multiple sclerosis, among other indications.\n Data suggests, that activation of the sigma-1 receptor is pivotal to restoring neural cell homeostasis and promoting neuroplasticity.1 This newest U.S. patent is expected to remain in force at least until 2037, not including any patent term extensions. Together with U.S. Patent No. 10,507,196 granted to Anavex in January 2020, the new patent will expand claim coverage for use of Anavex’s sigma-1 receptor agonists in oral, transdermal and parenteral compositions as well as for both pediatric and adult patients. \"This patent allowance by the USPTO is not only another important milestone in protecting the commercial potential of ANAVEX®2-73 (blarcamesine) and Anavex’s other lead compounds, but along with other recent allowances, demonstrates our strong overall commitment to protecting the innovation and commercial opportunity of our entire product portfolio,\" said Christopher U. Missling, PhD, President and Chief Executive Officer of Anavex. ANAVEX®2-73 (blarcamesine) is currently evaluated for Rett syndrome in one completed and two ongoing placebo-controlled clinical studies. In the U.S. Phase 2 study (ANAVEX®2-73-RS-001)2 adult Rett syndrome patients were treated with low-dose ANAVEX®2-73 (blarcamesine) oral liquid formulation, while the subsequent international AVATAR Phase 2 adult Rett syndrome study (ANAVEX®2-73-RS-002)3 and EXCELLENCE Phase 2/3 pediatric Rett syndrome study (ANAVEX®2-73-RS...