Business
Amylyx Pharmaceuticals Completes Negotiation Process and Signs Letter of Intent with the pCPA for ALBRIOZA™ for the Treatment of ALS
Amylyx will now work with federal, provincial, and territorial drug plans to ensure public coverage is available to eligible Canadians with ALS CAMBRIDGE,
About this update from Amylyx Pharmaceuticals, Inc.
[{"type":"text","content":"\nAmylyx will now work with federal, provincial, and territorial drug plans to ensure public coverage is available to eligible Canadians with ALS\n\n\n CAMBRIDGE, Mass.--(BUSINESS WIRE)--\nAmylyx Pharmaceuticals, Inc. (Nasdaq: AMLX) (“Amylyx” or the “Company”) today announced that it has completed the negotiation process and entered into a Letter of Intent (LOI) with the pan-Canadian Pharmaceutical Alliance (pCPA) for the terms and conditions under which ALBRIOZA™ (sodium phenylbutyrate and ursodoxicoltaurine) would qualify for reimbursement through federal, provincial, and territorial public drug plans for the treatment of amyotrophic lateral sclerosis (ALS).\n\n\n“Today marks a major milestone for people living with ALS and their caregivers in Canada. With this signed LOI, eligible Canadians living with this rapidly progressive disease who rely on public coverage are one step closer to accessing ALBRIOZA,” said Chris Aiello, General Manager and Head of Canada at Amylyx. “Our work is by no means done. We are now focused on the final task of translating this LOI into completed product listing agreements with each of the federal, provincial, and territorial jurisdictions to help ensure ALBRIOZA is listed on public formularies as soon as possible. This is a top priority given Canadians living with ALS simply do not have the time to wait.”\n\n\nALS is a relentlessly progressive and fatal neurodegenerative disease caused by motor neuron death in the brain and spinal cord that has a life expectancy of two to three years after symptom onset. Motor neuron loss in ALS leads to deteriorating muscle function, the inability to move and speak, respiratory paralysis, and eventually death. The CENTAUR clinical trial demonstrated that ALBRIOZA significantly slowed disease progression and loss of functional decline in people living with ALS, potentially giving them more time with functional independence. ALBRIOZA received approval with conditions from Health Canada in June 2022, marking the first regulatory approval for ALBRIOZA issued to Amylyx worldwide.\n\n\n“As a physician who treats people with ALS, access to treatments through public drug plans is critical for all those who may benefit,” said Dr. Angela Genge, Neurologist and Director of the ALS Clinic at the Montreal Neurological Institute-Hospital - The Neuro. “Being able to prescribe a...