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Amylyx Pharmaceuticals Announces Donated CENTAUR Clinical Trial Data Now Available to Help Advance Science in ALS for Future Treatments and Discoveries
CAMBRIDGE, Mass.--(BUSINESS WIRE)-- Amylyx Pharmaceuticals, Inc. today announced that the donated clinical data from the placebo arm of the CENTAUR clinical
About this update from Amylyx Pharmaceuticals, Inc.
[{"type":"text","content":" CAMBRIDGE, Mass.--(BUSINESS WIRE)--\nAmylyx Pharmaceuticals, Inc. today announced that the donated clinical data from the placebo arm of the CENTAUR clinical trial that evaluated the safety, efficacy, and survival benefits of AMX0035 in adult participants with amyotrophic lateral sclerosis (ALS) are now available in the Pooled Resource Open-Access ALS Clinical Trials (PRO-ACT) database. The PRO-ACT project is led by Alex Sherman at the Neurological Clinical Research Institute (NCRI) at Mass General Hospital and is currently sponsored by The ALS Association.\n\n“The only way we are going to find a cure for ALS is if the entire community shares data and builds upon the findings of others—that is how we can continue to move forward and develop innovative therapies to end ALS,” said Joshua Cohen and Justin Klee, Co-CEOs of Amylyx. “Continually adding to the database will give the ALS research community new information that could open up new pathways and approaches to developing new treatments. This platform also serves as an invaluable resource to analyze and validate the robustness of research data sets.”\n\nThe PRO-ACT database houses the largest ALS clinical trials dataset, containing more than 11,600 anonymized ALS participant records from 28 completed clinical trials. The platform harmonizes and merges data from existing publicly and privately conducted ALS clinical trials to generate a unique, freely available resource for the scientific community to find cures for ALS. The PRO-ACT platform was selected as the Bio-IT World’s Best Practices Awards winner in 2013 and The Clinical Informatics News Best Practices winner in the Clinical Data Intelligence category in 2016. In 2021, PRO-ACT won a prestigious Healey International Prize for Innovation in ALS for “enabling the new field of ALS predictive analytics.”\n\n\"The PRO-ACT database enables the type of collaboration necessary to accelerate the search for treatments and, ultimately, cures for ALS,” said Kuldip Dave, Ph.D., Senior Vice President of Research at the ALS Association. “By pooling resources and sharing data with researchers around the world, we move closer to creating a world without ALS.”\n\nThe PRO-ACT platform was created by Prize4Life, a non-profit organization, in partnership with the NEALS Consortium and the NCRI at Mass General Hospital, with funding from The ...