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Elto PharmaAppoints Paula Trzepacz, MD asChief Medical Advisor
Elto PharmaAppoints Paula Trzepacz, MD asChief Medical Advisor.
About this update from Amarantus Bioscience Holdings, Inc.
[{"type":"text","content":"\n\n Ex-Lilly Sr. Medical Fellow in Neurosciences to lead Parkinson's Phase 2b redesign NEW YORK, April 30, 2018 (GLOBE NEWSWIRE) --  via OTC PR WIRE -- Elto Pharma, Inc., a specialty pharmaceutical, clinical-stage wholly-owned subsidiary of Amarantus Bioscience Holdings, Inc. (OTCPK:AMBS) advancing Eltoprazine into a Phase 2b human clinical trial for the treatment of the orphan indication Parkinson's disease levodopa-induced dyskinesia (PD-LID), today announced the appointment of Paula Trzepacz, MD to the role of Chief Medical Advisor. In this role, Dr. Trzepacz will focus on assisting in the redesign of the Elto Pharma Phase 2b PD-LID protocol, as well as assisting Elto Pharma's interim management team in raising the capital necessary to prepare for the re-initiation of the Eltoprazine Phase 2b PD-LID clinical program. Dr. Trzepacz brings with her nearly 20 years of clinical development experience in the neurosciences.\n \"I am excited to join Elto Pharma and assist in the preparation for the Phase 2b clinical development program in Parkinson's disease,\" said Dr. Trzepacz, newly appointed Chief Medical Advisor at Elto Pharma. \"Eltoprazine has a robust safety package as a result of the extensive clinical research undertaken by Solvay (now Abbvie NYSE: ABBV), and has a compelling efficacy profile by virtue of the Phase 2a data published in the medical journal BRAIN in 2015 that clinically validated published pre-clinical data regarding the roles of the 5HT1a and 5HT1b receptors in PD-LID. Going forward, I will be working to complete the clinical development planning for Eltoprazine in PD-LID so that the program is in the best position possible to move rapidly into Phase 3 clinical development at the end of the planned Phase 2b. While I believe PD-LID is the appropriate lead indication for Eltoprazine by virtue of its orphan status, Eltoprazine also holds significant promise as a potential therapy in the areas of Agitation in Alzheimer's disease, as well as Adult Attention Deficit and Hyperactivity Disorder (Adult ADHD), both indications in which Eltoprazine has completed efficacy studies.\" Prior to joining Elto Pharma, Dr. Trzepacz was the Chief Medical Officer at Neurotrope from June 2016 to September 2016, and has served as a member of Amarantus' Alzheimer's disease Diagnostics Scientific Advisory Board since...