Business
Alnylam Announces 2020 Product and Pipeline Goals and Provides Updates at R&D Day
− Expects to Exceed Alnylam 2020 Goals with Four Marketed Products, 14 Organic Clinical Stage Programs, Including 6 in Late-Stage Development, Across 4
About this update from Alnylam Pharmaceuticals, Inc.
[{"type":"text","content":"\n− Expects to Exceed Alnylam 2020 Goals with Four Marketed Products, 14 Organic Clinical Stage Programs, Including 6 in Late-Stage Development, Across 4 Strategic Therapeutic Areas (STArs), by End of 2020 –\n\n\n– Initiates HELIOS-B Phase 3 Study of Investigational Vutrisiran in ATTR Amyloidosis Cardiomyopathy –\n\n\n– Announces Initial Positive Clinical Results with ALN-AAT02 and ALN-HBV02 (VIR-2218), Providing Human Proof of Concept for “Enhanced Stabilization Chemistry Plus” (ESC+) GalNAc Conjugate Delivery Technology –\n\n\n– Presents Initial Positive Clinical Data for ALN-AGT, an Investigational RNAi Therapeutic for Hypertension, Expanding Opportunities for RNAi Therapeutics in Highly Prevalent Chronic Diseases –\n\n\n– Reports Strong Progress in CNS and Ocular Delivery of RNAi Therapeutics with Seven Initial Programs Selected as Part of Regeneron Collaboration, Including ALN-HTT, an Investigational RNAi therapeutic for Huntington’s Disease –\n\n\n– Alnylam to Webcast its R&D Day Today at 8:00 a.m. ET –\n\n CAMBRIDGE, Mass.--(BUSINESS WIRE)--\nAlnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, is hosting an R&D Day in New York City today. During the event, the Company plans to discuss its commercial and R&D progress, including its product and pipeline goals for 2020, focusing on the potential for global approval and/or commercialization of four RNAi therapeutic products and the advancement of six late-stage investigational programs.\n\n\nAlnylam also announces today that it has initiated HELIOS-B, a global Phase 3 placebo-controlled mortality and cardiovascular hospitalization trial with investigational vutrisiran in patients with ATTR amyloidosis with cardiomyopathy. In addition, the Company is reporting initial positive clinical data with ALN-AAT02, ALN-HBV02 (VIR-2218), and ALN-AGT, representing the first human proof of concept for Alnylam’s ESC+ GalNAc conjugate delivery technology – having the potential to enable greater target selectivity and a wider therapeutic index – and expansion of the Alnylam pipeline in highly prevalent chronic disease opportunities. The Company is also reporting progress in its efforts with CNS and ocular delivery of RNAi therapeutics, including an update on the status of its collaborative work with Regeneron, and announces a new investigational CNS program, ...