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Aligos Therapeutics to Present Data on its Liver Disease Programs at the European Association for the Study of the Liver (EASL) Congress 2023
SOUTH SAN FRANCISCO, Calif., June 07, 2023 (GLOBE NEWSWIRE) -- Aligos Therapeutics, Inc. (Nasdaq: ALGS), a clinical stage biopharmaceutical company focused on
About this update from Aligos Therapeutics, Inc.
[{"type":"text","content":"SOUTH SAN FRANCISCO, Calif., June 07, 2023 (GLOBE NEWSWIRE) -- Aligos Therapeutics, Inc. (Nasdaq: ALGS), a clinical stage biopharmaceutical company focused on developing novel therapeutics to address unmet medical needs in liver and viral diseases, today announced that the company will present seven posters collectively highlighting data on its liver disease programs at the European Association for the Study of the Liver (EASL) Congress 2023, taking place in Vienna, Austria, June 21 – 24, 2023. “These presentations highlight the progress we have made advancing new potentially best-in-class compounds,” said Lawrence Blatt, Ph.D., MBA, Chairman & CEO of Aligos Therapeutics. “Each of these compounds represent a novel therapeutic strategy and we look forward to reporting additional findings at future meetings.” The abstracts were released today on the EASL website; the posters will contain additional information and will be made available to conference attendees at the beginning of the sessions during which the posters will be presented. The presentations will be available on the Scientific Presentations and Conferences page on Aligos’ corporate website following the meeting. Details from the abstracts released today are below: Chronic Hepatitis B CAM-E ALG-000184Abstract title: Treatment for up to 24 weeks with the capsid assembly modulator ALG-000184 results in dose related reductions in HBsAg in subjects with HBeAg positive chronic hepatitis BPresenter: Jinlin Hou, M.D.Summary: Dosing with ALG-000184 plus entecavir (ETV) for up to 24 weeks was well tolerated, exhibited predictable pharmacokinetics and resulted in substantial reductions in hepatitis B virus (HBV) DNA and hepatitis B surface antigen (HBsAg) compared to ETV alone. Dosing with ALG-000184 plus ETV resulted in dose-dependent, clinically relevant declines in HBsAg, suggesting a potential role of ALG-000184 in combination regimens for functional cure. siRNA ALG-125755Abstract title: Safety, pharmacokinetics, and antiviral activity of single ascending doses of ALG-125755, a GalNAc-conjugated small interfering RNA, in subjects with chronic hepatitis BPresenter: Alina Jucov, M.D., Ph.D.Summary: Single subcutaneous doses of 50 mg of ALG-125755, an siRNA designed to reduce hepatitis B surface antigen (HBsAg) in subjects with chronic hepatitis B (CHB), were shown to be well to...