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Aligos Therapeutics Presents 28-Day Safety, Efficacy and Pharmacokinetic Clinical Data for CAM Drug Candidate ALG-000184, First Clinical Data for NASH Drug Candidate ALG-055009 and Nonclinical Data in Other Chronic Hepatitis B Programs at the European...
Aligos Therapeutics Presents 28-Day Safety, Efficacy and Pharmacokinetic Clinical Data for CAM Drug Candidate ALG-000184, First Clinical Data for NASH Drug
About this update from Aligos Therapeutics, Inc.
[{"type":"text","content":"Aligos Therapeutics Presents 28-Day Safety, Efficacy and Pharmacokinetic Clinical Data for CAM Drug Candidate ALG-000184, First Clinical Data for NASH Drug Candidate ALG-055009 and Nonclinical Data in Other Chronic Hepatitis B Programs at the European Association for the Study of the Liver’s Digital International Liver Congress™ 2022 \n -Similar significant reductions of hepatitis B virus (HBV) DNA and HBV RNA observed following 28 days of daily oral ALG-000184 dosing, regardless of HBeAg status, across first four dosing chronic hepatitis B (CHB) patient cohorts-In the first clinical data presentation from our NASH program, preliminary data on multiple ascending doses of ALG-055009 in subjects with hyperlipidemia demonstrated favorable pharmacokinetics, safety, and anti-lipid activity-Presentations include nonclinical data from 2 other CHB programs SOUTH SAN FRANCISCO, Calif., June 22, 2022 (GLOBE NEWSWIRE) -- Aligos Therapeutics, Inc. (Nasdaq: ALGS), a clinical stage biopharmaceutical company focused on developing novel therapeutics to address unmet medical needs in viral and liver diseases, today announced that the company is presenting two posters showcasing preliminary Phase 1 data from its capsid assembly modulator (CAM) program in CHB and its thyroid hormone receptor-beta (THR-b) agonist in nonalcoholic steatohepatitis (NASH) at the European Association for the Study of the Liver Digital International Liver Congress™ 2022 (EASL ILC 2022). ILC 2022 is being held on June 22 - 26 at the ExCeL London Exhibition Centre in London, UK. The company is also presenting nonclinical data from two other drug classes within Aligos’ CHB portfolio: small interfering RNA (siRNA) and a small molecule PD-L1 inhibitor. The posters will be available on the “Scientific Presentation and Publications” page in the “Presentations” section of Aligos’ website at www.aligos.com. “We are pleased to continue demonstrating progress from across our chronic hepatitis B portfolio including small-molecule capsid assembly modulators, small interfering RNA molecules and small-molecule PD-L1 inhibitors. Our team is also proud to announce the first clinical data from our THR-b agonist in NASH,” said Lawrence Blatt, Ph.D., MBA, Chairman and CEO of Aligos. “In the context of CHB, we believe that a multi-part approach that addresses HBV viral replication, HBsAg red...