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Adaptive Biotechnologies Highlights New Data Showcasing the Clinical Utility of clonoSEQ® MRD Testing in Patients with Blood Cancers at the 64th ASH Annual Meeting
Multiple presentations reinforce clonoSEQ’s ability to provide valuable insights for treatment surveillance and clinical decision-makingMore than 30
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[{"type":"text","content":"Multiple presentations reinforce clonoSEQ’s ability to provide valuable insights for treatment surveillance and clinical decision-makingMore than 30 clonoSEQ-related abstracts to be presented at the meeting SEATTLE, Dec. 10, 2022 (GLOBE NEWSWIRE) -- Adaptive Biotechnologies Corporation (Nasdaq: ADPT), a commercial stage biotechnology company that aims to translate the genetics of the adaptive immune system into clinical products to diagnose and treat disease, today announced new data demonstrating the strengths of Adaptive’s next-generation sequencing (NGS)-based clonoSEQ® Assay in measuring minimal residual disease (MRD) in blood cancer patients. The data are being presented at the 64th Annual Meeting of the American Society of Hematology (ASH) taking place December 10-13, 2022. MRD refers to the small number of cancer cells that can remain in a patient’s body after treatment, which often cause no signs or symptoms but eventually can lead to recurrence of the disease. These residual cells can be present at very low levels and can only be identified by highly sensitive tests. clonoSEQ, which is the only FDA-cleared test for MRD assessment in lymphoid malignancies, is highly accurate, sensitive, and standardized compared to other technologies used for disease burden assessment. “Data at this year’s ASH meeting continue to show the benefits of serial MRD measurement for blood cancer patients both in routine patient care and in clinical trials,” said Nitin Sood, chief commercial officer, MRD, Adaptive Biotechnologies. \"Multiple studies presented at ASH reinforce that clonoSEQ MRD results can play an important role in some of the most challenging decisions clinicians must make on a daily basis, such as whether and when to stop treatment.\" Real-world evidence generated from the University of Alabama, Birmingham, demonstrated the feasibility of MRD testing with clonoSEQ to guide treatment decisions. The data were presented in a poster presentation titled, Induction Quadruplet Therapy and Minimal/Measurable Residual Disease (MRD)-Informed Treatment Adaptation in Newly Diagnosed Multiple Myeloma (NDMM): Results from an Academic-Community Pathway (Abstract 3593). The study adopted a modified treatment approach from the MASTER trial and evaluated 69 patients who were treated with the combination of daratumumab, Velcade, carfilzomib, len...