Business
Acumen Pharmaceuticals Reports Financial Results for First Quarter 2022 and Business Highlights
Topline results expected in the first half of 2023 from INTERCEPT-AD, a multi-center, randomized, double-blind, placebo-controlled, single- and
About this update from Acumen Pharmaceuticals, Inc.
[{"type":"text","content":"Topline results expected in the first half of 2023 from INTERCEPT-AD, a multi-center, randomized, double-blind, placebo-controlled, single- and multiple-ascending dose Phase 1 clinical trial of ACU193 in patients with early Alzheimer’s diseaseFrontiers in Neuroscience recently published a summary of preclinical evidence supporting the development of ACU193, a monoclonal antibody designed to selectively target toxic soluble amyloid-beta oligomers (AβOs), for the potential treatment of early Alzheimer’s disease$216.7 million in cash, cash equivalents and marketable securities as of March 31, 2022, which is expected to provide cash runway through 2025 Company to host conference call and webcast today at 4:30 pm ET CHARLOTTESVILLE, Va. and CARMEL, Ind., May 16, 2022 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ: ABOS), a clinical-stage biopharmaceutical company focused on the development of novel targeted therapeutics for Alzheimer’s disease (AD), today reported financial results for the quarter ended March 31, 2022 and provided a business update. “During the first quarter, we made significant progress in advancing INTERCEPT-AD, our Phase 1 clinical trial investigating the safety, tolerability, pharmacokinetics and target engagement of ACU193 in patients with early AD. We expect to report topline results in the first half of 2023,” said Daniel O’Connell, President and Chief Executive Officer of Acumen. “Further, we expect our existing cash, cash equivalents and marketable securities will be sufficient to fund our operating expenses and capital expenditure requirements through 2025 based on our current plans.” The Acumen team is pleased with the recent publication of the Frontiers in Neuroscience article in which preclinical evidence characterizing ACU193’s selectivity and differentiated profile is reviewed with the rationale for targeting soluble amyloid-beta oligomers in early AD. “The Frontiers article is timely, as we and others in the field look at upcoming clinical and regulatory events and as we continue to position ACU193 as potentially having a best-in-class treatment profile based on its potential safety, including anticipated limited to no ARIA-E, and clinical benefits on cognitive measures,” said Eric Siemers, Acumen’s Chief Medical Officer. “Each other monoclonal antibody which is approved or is in development...