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Acrivon Therapeutics to Participate on a Panel at Cowen’s 43rd Annual Health Care Conference
CEO to participate on ovarian cancer panel and will highlight ACR-368, a DNA Damage Response (DDR) inhibitor in clinical testing for platinum-resistant
About this update from Acrivon Therapeutics, Inc.
[{"type":"text","content":"CEO to participate on ovarian cancer panel and will highlight ACR-368, a DNA Damage Response (DDR) inhibitor in clinical testing for platinum-resistant advanced ovarian cancer and other solid tumors\nWATERTOWN, Mass., Feb. 27, 2023 (GLOBE NEWSWIRE) -- Acrivon Therapeutics, Inc. (“Acrivon” or “Acrivon Therapeutics”) (Nasdaq: ACRV), a clinical stage biopharmaceutical company developing precision oncology medicines that it matches to patients whose tumors are predicted to be sensitive to each specific medicine by utilizing its proprietary proteomics-based patient responder identification platform, today announced the company’s chief executive officer and president, Peter Blume-Jensen, M.D., Ph.D., will participate in a corporate panel discussion on ovarian cancer on Wednesday, March 8, 2023 at 9:10 a.m. ET at the Cowen 43rd Annual Health Care Conference in Boston. To access the live webcast of this panel, visit the Events & Presentations page within the investor section of the company’s website at https://ir.acrivon.com/news-events/events-presentations. A replay of the webcast will be available via the same link for 90 days following the panel. ACR-368 Phase 2 Study The Phase 2, multicenter, open-label clinical trial is initially evaluating ACR-368 in single-arm, potentially registrational studies of ovarian cancer, endometrial adenocarcinoma, or platinum-resistant urothelial cancers based on predicted sensitivity to ACR-368. For ovarian cancer, it will enroll patients with histologically confirmed, platinum resistant, advanced (metastatic and/or unresectable) high-grade serous/endometrioid ovarian, primary peritoneal, or fallopian tube cancer. Ovarian cancer patients must have received at least 1, but can have had up to 6, prior lines of systemic therapy. Using the company’s proprietary OncoSignature® predictive test, patients of all three tumor types will be allocated to one of two treatment arms. Patients who test positive for predicted sensitivity to ACR-368 monotherapy will be enrolled into single-arm, potentially registrational Phase 2 studies to assess primarily the anti-tumor activity (confirmed overall response rate) of the recommended Phase 2 dose of ACR-368 (105 mg/m2). Patients who are negative on the OncoSignature® test will be enrolled in an exploratory single-arm Phase 1b/2 study of the combination of the recommended...