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Achieve Life Sciences Announces Last Subject Last Visit Completed in Phase 2 ORCA-V1 Trial of Cytisinicline for e-Cigarette Cessation
Topline Data Expected in 2Q 2023 SEATTLE, Wash. and VANCOUVER, British Columbia, March 08, 2023 (GLOBE NEWSWIRE) -- Achieve Life Sciences, Inc. (NASDAQ:
About this update from Achieve Life Sciences, Inc.
[{"type":"text","content":"Topline Data Expected in 2Q 2023\nSEATTLE, Wash. and VANCOUVER, British Columbia, March 08, 2023 (GLOBE NEWSWIRE) -- Achieve Life Sciences, Inc. (NASDAQ: ACHV), a late-stage clinical pharmaceutical company committed to the global development and commercialization of cytisinicline for smoking cessation and nicotine dependence, today announced that the last study follow-up visit for the last subject enrolled in the Phase 2 ORCA-V1 trial has occurred.ORCA-V1 is evaluating the efficacy and safety of cytisinicline in adult users of nicotine e-cigarettes, or vapes, and is being supported in part through grant funding from the National Institute on Drug Abuse (NIDA) of the National Institutes of Health (NIH).“We are excited to have reached this important milestone in the ORCA-V1 trial, bringing us one step closer to understanding the cessation potential of cytisinicline in users of nicotine e-cigarettes who desire to quit,” stated John Bencich, Chief Executive Officer of Achieve. “We look forward to reporting topline results in the second quarter of this year from both the ORCA-V1 trial, and separately from ORCA-3, our second Phase 3 trial in smoking cessation.”The ORCA-V1 trial randomized 160 adult users of nicotine e-cigarettes across 5 clinical trial locations in the United States. Participants were randomized 2 to 1 to receive either 3 mg of cytisinicline three times daily or placebo three times daily, for a period of 12 weeks. Patients also received standardized behavioral support throughout the trial. The primary endpoint is continuous abstinence during the final 4 weeks of treatment. Dr. Nancy Rigotti, Professor of Medicine at Harvard Medical School and Director, Tobacco Research and Treatment Center, Massachusetts General Hospital is the primary investigator for the ORCA-V1 trial.For more information on cytisinicline or the ORCA-V1 trial, please visit www.achievelifesciences.com.The research and clinical study discussed in this press release is supported by the National Institute on Drug Abuse (NIDA) of the National Institutes of Health (NIH) under Award Number 4R44DA054784-02. The content is the sole responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.About Achieve and Cytisinicline Achieve’s focus is to address the global smoking health and nicotine addictio...