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Acadia Pharmaceuticals Presents New Dementia-Related Psychosis Real-World Outcomes Data at Psych Congress 2021
- Analyses indicate ongoing need for approved treatments with favorable benefit-risk profile for treating patients with dementia-related hallucinations and
About this update from Acadia Pharmaceuticals Inc.
[{"type":"text","content":"\n- Analyses indicate ongoing need for approved treatments with favorable benefit-risk profile for treating patients with dementia-related hallucinations and delusions\n\n SAN DIEGO--(BUSINESS WIRE)--\nAcadia Pharmaceuticals Inc. (Nasdaq: ACAD) announced today that three data presentations featuring new analyses of Medicare claims data on dementia-related psychosis (DRP) outcomes were presented at Psych Congress 2021, held virtually and in-person October 29-November 1, 2021 in San Antonio, TX. The presentations demonstrate the suboptimal outcomes associated with the off-label use of currently available atypical antipsychotic treatments in managing dementia-related hallucinations and delusions, along with the related cost burdens.\n\n“The suboptimal outcomes and costs associated with off-label use of dopaminergic atypical antipsychotics underscore the challenges health care providers face in appropriately treating patients with dementia-related psychosis, including hallucinations and delusions,” said Ponni Subbiah, M.D., M.P.H., Senior Vice President, Global Head of Medical Affairs and Chief Medical Officer at Acadia.\n\nDetails of the posters presented are as follows:\n\nPoster: Treatment Emergent Adverse Events and Associated Adverse Event-Specific Per-Patient-Per-Year Costs: Analysis of Medicare Beneficiaries Treated with Off-Label Atypical Antipsychotics for Dementia-Related Psychosis: Data from a Medicare claims analysis of 23,267 patients with dementia-related psychosis initiating atypical antipsychotic monotherapy from January 2014 through December 2017 showed that over 70% had one or more adverse events (AEs) within one year, with 64% experiencing dyslipidemia, 50% experiencing peripheral vascular disease (PVD) and 40% experiencing cerebrovascular adverse events (CVAEs) such as stroke and transient ischemic attacks. Median per-patient-per-year (PPPY) costs of hyperlipidemia, PVD, and CVAE were $5,565, $227 and $3,682, respectively.\n\nPoster: Incremental Cost of Treatment Emergent Falls/Fractures, Stroke and Cerebrovascular Adverse Events Among Patients on Atypical Antipsychotics: Analysis of Medicare Patients with Dementia-Related Psychosis: A Medicare claims analysis of 23,267 treated DRP patients showed approximately one in five patients experienced falls/fractures or stroke (23% and 17%, respectively) while nearly two...