Press release
Absci Expands ABS-201 Scientific Advisory Board with Addition of Leading Dermatology Experts Dr. Rodney Sinclair and Dr. David Goldberg
World-renowned experts will guide the clinical development of ABS-201, a therapeutic antibody entering clinical trials for the treatment of androgenetic
About this update from Absci Corporation
[{"type":"text","content":"World-renowned experts will guide the clinical development of ABS-201, a therapeutic antibody entering clinical trials for the treatment of androgenetic alopecia.\nVANCOUVER, Wash. and NEW YORK, Aug. 25, 2025 (GLOBE NEWSWIRE) -- Absci (Nasdaq: ABSI), a clinical-stage biotech company advancing breakthrough therapeutics with generative AI, today announced that world-renowned dermatologists Dr. Rodney Sinclair and Dr. David Goldberg have joined its ABS-201 Scientific Advisory Board. They will guide the scientific and clinical development of ABS-201, Absci’s flagship, AI-designed therapeutic program for androgenetic alopecia. Androgenetic alopecia, commonly known as male-pattern or female-pattern hair loss, affects approximately 80 million Americans alone. The condition causes crown balding and receding hairlines in men, and progressive hair thinning in women. Currently, the only FDA-approved treatments—minoxidil and finasteride—show limited efficacy and notable side effects, leaving patients with limited therapeutic options. ABS-201 represents a novel therapeutic approach targeting prolactin receptors to stimulate hair follicle regeneration and promote durable hair regrowth as demonstrated in in vivo studies. In preclinical studies, the antibody demonstrated statistically significant superior hair regrowth compared to minoxidil in pre-clinical mouse models. Phase 1/2a clinical trials are planned to begin in early 2026, with initial proof-of-concept data expected in the second half of 2026. \"Dr. Sinclair and Dr. Goldberg bring world-class expertise to our hair-regrowth program,” said Sean McClain, Founder and CEO of Absci. “Their deep understanding of androgenetic alopecia and its treatment challenges will be invaluable as we rapidly advance ABS-201 toward clinical validation as a potential best-in-class therapy.\" Dr. Rodney Sinclair, MBBS, MD, FACD, is the Professor of Dermatology at the University of Melbourne and Director of Sinclair Dermatology in Melbourne. He is a world-renowned expert in hair loss, with over three decades dedicated to research, clinical practice, and patient advocacy. Dr. Sinclair has authored over 1000 publications including contributions to key textbooks in dermatology and hair disorders. \"Having researched hair loss for over three decades, I've seen the substantial impact androgenetic alopecia has on pa...