Spyre Therapeutics, Inc. · NASDAQ:SYRE
Spyre Therapeutics, Inc. shareholders
As of Jun 30, 2026, 251 institutions reported holding Spyre Therapeutics, Inc. Largest: Fidelity, BlackRock and Vanguard. New holders, exits, insiders and big stakes, each with its filing.
| Holder | Shares | % of Spyre Therapeutics, Inc. | Change | Filed |
|---|---|---|---|---|
| Fidelity | 13M | +1.25M | Aug 13, 2026 | |
| BlackRock | 6.51M | +985K | Aug 7, 2026 | |
| Vanguard | 6.42M | +2.23M | Aug 13, 2026 | |
| Perceptive Advisors LLC | 4.32M | +536K | Aug 14, 2026 | |
| Rtw Investments, LP | 4.25M | +80,000 | Aug 14, 2026 | |
| Paradigm Biocapital Advisors LP | 3.84M | +1.88M | Aug 14, 2026 | |
| Capital Group | 3.27M | +858K | Aug 12, 2026 | |
| State Street | 3.06M | +450K | Aug 7, 2026 | |
| Venrock Adviser, LLC | 2.99M | −700K | Aug 14, 2026 | |
| T. Rowe Price | 2.96M | +1.36M | Aug 14, 2026 |