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<title>Simcere Pharmaceutical Group Ltd — News on 6ix</title>
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<title>Boehringer Ingelheim and Simcere partner to advance a dual-target antibody treatment to address unmet needs in inflammatory bowel disease</title>
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<pubDate>Tue, 27 Jan 2026 10:40:00 GMT</pubDate>
<description>Simcere Pharmaceutical Group Ltd. ("Simcere") (HKEX: 2096) and Boehringer Ingelheim, today announced a license and collaboration agreement to develop SIM0709, a pre-clinical TL1A/IL23p19 bispecific antibody from Simcere, for the treatment of inflammatory bowel disease (IBD).</description>
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<title>Simcere's IL-2 Mutant Fusion Protein SIM0278 Entered Phase II Clinical Trial Stage</title>
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<pubDate>Mon, 10 Nov 2025 12:06:00 GMT</pubDate>
<description>Simcere Pharmaceutical Group (2096.HK) announced that its regulatory T cells(Treg)-preferential IL-2 mutant Fc fusion protein (IL-2 mu-Fc), SIM0278, has officially entered a Phase II clinical study in China for the treatment of moderate-to-severe atopic dermatitis (AD). The first dose was achieved in Hangzhou First People's Hospital.</description>
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<title>Simcere Zaiming Announces First Patient Dosed in the US in a Phase 1 Trial of Trispecific Antibody SIM0500 in Patients with Relapsed/Refractory Multiple Myeloma</title>
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<pubDate>Thu, 19 Jun 2025 00:37:00 GMT</pubDate>
<description>Simcere Zaiming, an innovative oncology-focused subsidiary of Simcere Pharmaceutical Group (2096.HK) today announced the first US patient has started treatment in the ongoing Phase 1 trial (SIM0500-101, NCT06375044) at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai, evaluating safety, tolerability, pharmacokinetics and preliminary efficacy of SIM0500 in patients with relapsed/refractory multiple myeloma (RRMM).</description>
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