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<title>Painreform Ltd — News on 6ix</title>
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<title>Painreform Ltd</title>
<link>https://6ix.com/company/painreform-ltd</link>
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<title>PRF Technologies Announces FDA Clearance of IND Application for OcuRing™-K Phase II Clinical Trial</title>
<link>https://6ix.com/company/painreform-ltd/news/prf-technologies-announces-fda-clearance-of-ind-application-for-ocuringtm-k-phase-ii-clinical-trial</link>
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<pubDate>Tue, 28 Apr 2026 12:00:00 GMT</pubDate>
<description>Milestone supports advancement of PRF’s drop-less ocular drug-delivery platform into next-stage U.S. clinical development for post-cataract pain and inflammationTEL AVIV, Israel, April 28, 2026 (GLOBE NEWSWIRE) -- PRF Technologies Ltd. (Nasdaq: PRFX) (“PRF” or the “Company”), a clinical-stage specialty pharmaceutical company focused on reformulating established therapeutics for post-operative pain management, together with its majority-owned subsidiary LayerBio, Inc., today announced that the U.</description>
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<title>PRF Technologies Ltd. Announces Commercial Collaboration Agreement with Blade Ranger to Accelerate Large-Scale DeepSolar Commercial Engagements</title>
<link>https://6ix.com/company/painreform-ltd/news/prf-technologies-ltd-announces-commercial-collaboration-agreement-with-blade-ranger-to-accelerate-large-scale-deepsolar-commercial-engagements</link>
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<pubDate>Tue, 17 Mar 2026 12:30:00 GMT</pubDate>
<description>Targeting Multiple 150MW+ Enterprise Solar Deployments Through Established Global Renewable Energy NetworkTEL AVIV, Israel, March 17, 2026 (GLOBE NEWSWIRE) -- PRF Technologies Ltd. (Nasdaq: PRFX) (“PRF” or the “Company”) today announced a commercial collaboration agreement with Blade Ranger Ltd. (TASE: BLRN) designed to accelerate the commercial expansion of its DeepSolar platform across utility-scale solar portfolios. The commercial collaboration agreement is structured to support the introduct</description>
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<title>PRF Technologies’ DeepSolar Announces its First Commercial Due Diligence Engagement with EDF Power Solutions Israel, a Global Leader in Renewable Energy</title>
<link>https://6ix.com/company/painreform-ltd/news/prf-technologies-deepsolar-announces-its-first-commercial-due-diligence-engagement-with-edf-power-solutions-israel-a-global-leader-in-renewable-energy</link>
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<pubDate>Wed, 18 Feb 2026 14:15:00 GMT</pubDate>
<description>Agreement Initiates Data-Driven Technical Due Diligence of an Operational, Utility-Scale Solar Asset in IsraelTEL AVIV, Israel, Feb. 18, 2026 (GLOBE NEWSWIRE) -- PRF Technologies Ltd. (Nasdaq: PRFX) (“PRF” or the “Company”) (formerly “PainReform”) today announced that its DeepSolar business unit has entered into a solar analytics services agreement with a subsidiary of EDF Group (Electricite’ De France, France’s Electric Company, one of the largest international energy companies), a global leade</description>
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<title>PRF Technologies Wins Another European Utility-Scale Solar Deployment, Expanding DeepSolar’s Installed Commercial Base</title>
<link>https://6ix.com/company/painreform-ltd/news/prf-technologies-wins-another-european-133000500</link>
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<pubDate>Wed, 11 Feb 2026 13:30:00 GMT</pubDate>
<description>Shikun & Binui Energy Selects DeepSolar SaaS Starting with a 71 MW Solar Project, Reinforcing Adoption by European Infrastructure OperatorsTEL AVIV, Israel, Feb. 11, 2026 (GLOBE NEWSWIRE) -- PRF Technologies (Nasdaq: PRFX) (“PRF” or the “Company”), through its DeepSolar™ AI-driven solar analytics business unit, today announced the signing of a software-as-a-service (SaaS) agreement with Shikun & Binui Energy for the deployment of DeepSolar at the 71 megawatt (MW) Satu Mare photovoltaic site in R</description>
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<title>PRF Technologies Files Its First Patent Application for Solar Plant Micro-Climate Forecast Modeling Designed to Improve Energy Production Forecast Accuracy</title>
<link>https://6ix.com/company/painreform-ltd/news/prf-technologies-files-first-patent-140500726</link>
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<pubDate>Tue, 20 Jan 2026 14:05:00 GMT</pubDate>
<description>Patent filing follows acceptance into the NVIDIA Connect Program Proprietary software targets weather forecast-driven revenue optimization, reduced penalty risk, and improved market performance for utility-scale solar assets TEL AVIV, Israel, Jan. 20, 2026 (GLOBE NEWSWIRE) -- PRF Technologies Ltd. (Nasdaq: PRFX) (“PRF” or the “Company”) (formerly “PainReform”) today announced that it has filed a patent application covering proprietary methods for solar plant–level micro-climate modeling designed</description>
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<title>PainReform Ltd. Changes Name to PRF Technologies Ltd. Reflecting Expansion into Diversified Healthcare and AI-Driven Energy Platforms</title>
<link>https://6ix.com/company/painreform-ltd/news/painreform-ltd-changes-name-prf-210500625</link>
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<pubDate>Thu, 15 Jan 2026 21:05:00 GMT</pubDate>
<description>Shareholders Approved Name Change at January 6, 2026 Annual General Meeting as Company Evolves Beyond Single-Asset FocusTEL AVIV, Israel, Jan. 15, 2026 (GLOBE NEWSWIRE) -- PRF Technologies Ltd. (Nasdaq: PRFX) (“PRF” or the “Company”) (formerly “PainReform”) today announced its corporate name change to PRF Technologies Ltd. following shareholder approval at the Company’s Annual General Meeting held on Tuesday, January 6, 2026. The Company’s Nasdaq ticker symbol will remain PRFX. The approved name</description>
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<title>PainReform’s LayerBio’s Drop-Less OcuRing™-K Delivery Platform Demonstrates Favorable Safety Profile in Preclinical and Phase I Clinical Studies</title>
<link>https://6ix.com/company/painreform-ltd/news/painreform-layerbio-drop-less-ocuring-140000429</link>
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<pubDate>Mon, 12 Jan 2026 14:00:00 GMT</pubDate>
<description>Phase I human study and preclinical evaluations of OcuRing™-K showed no treatment-related safety concerns, supporting advancement toward IND submissionTEL AVIV, Israel, Jan. 12, 2026 (GLOBE NEWSWIRE) -- PainReform Ltd. (Nasdaq: PRFX), a clinical-stage specialty pharmaceutical company focused on reformulating established therapeutics for post-operative pain management, together with its majority-owned subsidiary LayerBio, Inc., today announced safety data supporting the continued development of O</description>
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<title>PainReform’s DeepSolar Launches Smart TDD, a Next-Generation Solar Due Diligence Service Targeting the $60B+ Global Solar Asset M&A Market</title>
<link>https://6ix.com/company/painreform-ltd/news/painreform-deepsolar-launches-smart-tdd-140000415</link>
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<pubDate>Mon, 05 Jan 2026 14:00:00 GMT</pubDate>
<description>New lifecycle-wide audit platform provides complete data coverage, advanced diagnostics, and rapid turnaround, supporting investors, operators, insurers and lenders across commissioning, underperformance, warranty expiry, and asset transactionsTEL AVIV, Israel, Jan. 05, 2026 (GLOBE NEWSWIRE) -- PainReform Ltd. (Nasdaq: PRFX) today announced that its DeepSolar business unit has launched Smart TDD, an advanced solar Technical Due Diligence (“TDD”) service designed to provide faster, more accurate,</description>
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<title>BladeRanger to Showcase Advanced Green Energy Technologies at Abu Dhabi Sustainability Week</title>
<link>https://6ix.com/company/painreform-ltd/news/bladeranger-to-showcase-advanced-green-energy-technologies-at-abu-dhabi-sustainability-week</link>
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<pubDate>Tue, 30 Dec 2025 13:48:00 GMT</pubDate>
<description>BladeRanger (TASE: BLRN), a provider of drone-based inspection, maintenance, and AI-driven analytics solutions for green energy and critical infrastructure, today announced its participation in Abu Dhabi Sustainability Week (ADSW), a leading global platform dedicated to sustainability, clean energy, and climate-related innovation.</description>
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<title>PainReform Confirms the Ability of Its LayerBio Drop-Less Sustained-Release Ocular Platform to Accommodate Multiple Drug Entities</title>
<link>https://6ix.com/company/painreform-ltd/news/painreform-confirms-ability-layerbio-drop-133000343</link>
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<pubDate>Wed, 10 Dec 2025 13:30:00 GMT</pubDate>
<description>R&D assessment shows the platform can incorporate different drug entities onto its sustained-release matrix, supporting long-term potential to reduce or eliminate reliance on medicated eye dropsTEL AVIV, Israel, Dec. 10, 2025 (GLOBE NEWSWIRE) -- PainReform Ltd. (Nasdaq: PRFX) today announced that its pharmaceutical division has completed an R&D assessment of LayerBio’s proprietary drop-less, sustained-release ocular drug-delivery platform. The assessment confirmed that its sustained release, pol</description>
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<title>PainReform Commences Development for OcuRing™-K Phase II Trial, LayerBio’s Drop-Less Sustained-Release Ocular Therapy</title>
<link>https://6ix.com/company/painreform-ltd/news/painreform-commences-development-ocuring-k-141500963</link>
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<pubDate>Tue, 02 Dec 2025 14:15:00 GMT</pubDate>
<description>Development plan positions OcuRing™-K for advancement in the fast-growing, multi-billion-dollar global cataract surgery marketTEL AVIV, Israel, Dec. 02, 2025 (GLOBE NEWSWIRE) -- PainReform Ltd. (Nasdaq: PRFX) today announced, through its pharmaceutical division, the commencement of its development plan for OcuRing™-K, LayerBio’s patented, drop-less, intraoperatively administered sustained-release ocular therapy designed to deliver controlled, site-specific release of ketorolac following cataract</description>
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<title>PainReform’s DeepSolar Advances Development of its AI-Driven Automated Reporting Engine for Solar-Asset Analysis</title>
<link>https://6ix.com/company/painreform-ltd/news/painreform-deepsolar-advances-development-ai-140000114</link>
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<pubDate>Wed, 12 Nov 2025 14:00:00 GMT</pubDate>
<description>TEL AVIV, Israel, Nov. 12, 2025 (GLOBE NEWSWIRE) -- PainReform Ltd. (Nasdaq: PRFX) today announced that DeepSolar, its solar energy business unit developing next-generation AI analytics, has advanced the development of its proprietary automated reporting engine, designed to transform how solar-asset performance is analyzed, understood, and communicated. The automated reporting engine reduces manual effort and produces tailored reports according to the customers’ needs. Performance reports are es</description>
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<title>PainReform’s DeepSolar, Developing “DeepSolar Predict” within the NVIDIA Connect Program, Featured in The Market Link’s “Watchlist Interview” and Announces Progress Toward Pilot Projects</title>
<link>https://6ix.com/company/painreform-ltd/news/painreform-deepsolar-developing-deepsolar-predict-133000589</link>
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<pubDate>Wed, 05 Nov 2025 13:30:00 GMT</pubDate>
<description>TEL AVIV, Israel, Nov. 05, 2025 (GLOBE NEWSWIRE) -- PainReform Ltd. (Nasdaq: PRFX), today announced that DeepSolar, its solar energy business unit developing next-generation AI-driven solar analytics, was recently featured in a Watchlist Interview produced in collaboration with The Market Link, highlighting its participation in the NVIDIA Connect program. The interview features key elements of DeepSolar Predict that are attracting interest from potential partners and customers, reflecting the gr</description>
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<title>PainReform Provides Business Update for the Six Months Ended June 30, 2025</title>
<link>https://6ix.com/company/painreform-ltd/news/painreform-provides-business-six-months-132700909</link>
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<pubDate>Wed, 01 Oct 2025 13:27:00 GMT</pubDate>
<description>TEL AVIV, Israel, Oct. 01, 2025 (GLOBE NEWSWIRE) -- PainReform Ltd. (Nasdaq: PRFX), a specialty pharmaceutical company focused on the reformulation of established therapeutics and commercialization of AI-driven solar analytics technologies, today provided a business update for the six months ended June 30, 2025. Key Highlights: Completed majority investment in LayerBio, adding OcuRing™-K, a breakthrough dropless cataract therapy targeting a ~$9B global marketAdvanced PRF-110 with ongoing R&D fol</description>
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<title>PainReform/DeepSolar Accepted into NVIDIA Connect Program</title>
<link>https://6ix.com/company/painreform-ltd/news/painreform-deepsolar-accepted-nvidia-connect-123000460</link>
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<pubDate>Tue, 19 Aug 2025 12:30:00 GMT</pubDate>
<description>Acceptance to NVIDIA Connect Program offers access to unique tools for the development of DeepSolar’s nextgen, AI-driven, solar forecasting platform to improve weather prediction accuracy by up to 50% and optimize energy asset performanceTEL AVIV, Israel, Aug. 19, 2025 (GLOBE NEWSWIRE) -- PainReform Ltd. (Nasdaq: PRFX), today announced that DeepSolar, PainReform’s solar energy business unit developing next-generation AI-driven solar analytics, has been accepted into the prestigious NVIDIA Connec</description>
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<title>PainReform Ltd. Completes Strategic Investment in LayerBio to Enter $9B Global Cataract Surgery Market with Breakthrough Non-Opiate, Non-Steroidal Postoperative NSAID Drug Delivery System</title>
<link>https://6ix.com/company/painreform-ltd/news/painreform-ltd-completes-strategic-investment-123000946</link>
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<pubDate>Wed, 13 Aug 2025 12:30:00 GMT</pubDate>
<description>Acquisition of Majority Equity Interest in LayerBio and its OcuRing™-K Technology Targets Growing Demand for ‘Dropless’ Solutions in Ophthalmic SurgeryTEL AVIV, Israel, Aug. 13, 2025 (GLOBE NEWSWIRE) -- PainReform Ltd. (Nasdaq: PRFX), today announced, through its pharmaceutical division, the closing of its previously announced investment in LayerBio, Inc., a privately held Boston-based biotechnology company advancing sustained-release drug delivery technologies in ophthalmology. With this transa</description>
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<title>PainReform Ltd. enters into a Strategic Investment Agreement to Expand its Non-Opiate Pain Management Pipeline into Opthamology with LayerBio</title>
<link>https://6ix.com/company/painreform-ltd/news/painreform-ltd-enters-strategic-investment-123000346</link>
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<pubDate>Thu, 10 Jul 2025 12:30:00 GMT</pubDate>
<description>This Investment will add a differentiated ophthalmic platform, targeting an estimated 3 million annual U.S. cataract surgeries with long-acting, “dropless” pain and inflammation treatmentTEL AVIV, Israel, July 10, 2025 (GLOBE NEWSWIRE) -- PainReform Ltd. (Nasdaq: PRFX), today announced, through its pharmaceutical division, the signing of a strategic investment agreement with LayerBio Inc., a privately held Boston biotechnology company developing proprietary, long-acting, non-opiate treatments fo</description>
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<title>Blade Ranger: Consideration from PainReform Transaction Continues to Mature Following Growth in Software Sales</title>
<link>https://6ix.com/company/painreform-ltd/news/blade-ranger-consideration-from-painreform-transaction-continues-to-mature-following-growth-in-software-sales</link>
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<pubDate>Tue, 27 May 2025 16:12:00 GMT</pubDate>
<description>Blade Ranger Ltd. (TASE: BLRN), a company listed on the Tel Aviv Stock Exchange, announced the achievement of a first milestone in the transaction involving the sale of its DeepSolar operations to PainReform (NASDAQ: PRFX).</description>
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<title>PainReform Launches Strategic AI Pilot with Econergy Using Its Proprietary DeepSolar™ Platform to Optimize One of Romania’s Largest Solar Projects</title>
<link>https://6ix.com/company/painreform-ltd/news/painreform-launches-strategic-ai-pilot-203000392</link>
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<pubDate>Wed, 07 May 2025 20:30:00 GMT</pubDate>
<description>TEL AVIV, Israel, May 07, 2025 (GLOBE NEWSWIRE) -- PainReform Ltd. (Nasdaq: PRFX), today announced the launch of a strategic pilot program with Econergy Renewable Energy Ltd., a leading European independent power producer (IPP). The project will utilize PainReform’s proprietary DeepSolar™ platform, an AI-powered optimization solution designed to enhance operational efficiency and energy yield at utility-scale solar facilities. The pilot will be conducted at Econergy’s 92-megawatt (MW) photovolta</description>
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<title>PainReform Expands into Home Energy Management Sector, Leveraging DeepSolar’s AI-Driven Platform to Address the Growing Solar Optimization Market</title>
<link>https://6ix.com/company/painreform-ltd/news/painreform-expands-home-energy-management-123000815</link>
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<pubDate>Thu, 10 Apr 2025 12:30:00 GMT</pubDate>
<description>TEL AVIV, Israel, April 10, 2025 (GLOBE NEWSWIRE) -- PainReform Ltd. (Nasdaq: PRFX), a clinical-stage specialty pharmaceutical company and developer of AI-powered energy optimization technologies, today announced its official expansion into the rapidly growing Smart Energy Management (SEM) sector. This move follows the successful acquisition of DeepSolar, a cutting-edge provider of AI-driven software solutions designed to optimize solar energy usage in residential and utility-scale solar power p</description>
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