Nippon Shinyaku : Notice Regarding Executive Personnel Changes

(1) Newly Appointed Director

Mitsuharu Koizumi Head of Sales and Marketing Planning Division (Current)

(2) Reappointed Director

Shigenobu Maekawa Representative Director, Chairman (Current)

Toru Nakai Representative Director, President (Current)

Takanori Edamitsu Director, Business Management & Sustainability (Current)

Hitoshi Ishizawa Director, Functional Food (Current)

Hitomi Kimura Director, Resource Procurement, production and Assurance (Current)

Kazuyuki Iwata Director, Sales and Marketing (Current)

Keiichi Kuwano Director, Research & Development (Current)

Yoshinao Wada Outside Director (Current)

Yukari Kobayashi Outside Director (Current)

Mayumi Nishi Outside Director (Current)

Yohtaro Hongo Outside Director (Current)

(3) Director Scheduled for Promotion

Scheduled to Be Promoted to Managing Director

Takanori Edamitsu Director, Business Management & Sustainability (Current)

(4) Director Scheduled to Retire

Takashi Takaya Director, Personnel, General Affairs, Risk Management,

Compliance & Digital Transformation (Current)

For Reference:

Composition of the Board of Directors and Audit & Supervisory Board Members After the Annual General Meeting of Shareholders Scheduled for Late June 2026.

Shigenobu Maekawa Representative Director, Chairman

Toru Nakai Representative Director, President

Takanori Edamitsu Managing Director, Business Management & Sustainability

Hitoshi Ishizawa Director, Functional Food

Hitomi Kimura Director, Resource Procurement, production and Assurance

Kazuyuki Iwata Director, Sales and Marketing

Keiichi Kuwano Director, Research & Development

Mitsuharu Koizumi Director, Personnel, General Affairs, Risk Management,

Compliance & Digital Transformation

Yoshinao Wada Outside Director

Yukari Kobayashi Outside Director

Mayumi Nishi Outside Director

Hirotsugu Ito Standing Audit & Supervisory Board Member

Eriko Doi Standing Audit & Supervisory Board Member

Hiroharu Hara Outside Audit & Supervisory Board Member

Mariko Chaki Outside Audit & Supervisory Board Member

The Representative Director, Directors with designated titles, and Executive Directors will be appointed at a meeting of the Board of Directors scheduled to be held on the day of the Annual General Meeting of Shareholders.