X0609 4 2026-10-13 0001674416 CRISPR Therapeutics AG CRSP 0001682019 Kulkarni Samarth false C/O CRISPR THERAPEUTICS 105 WEST FIRST STREET BOSTON MA 02127 true true false false Chief Executive Officer false Common Shares 2026-10-13 4 M false 8333 A 263834 D Common Shares 2026-10-14 4 S false 4098 49.26 D 259736 D Restricted Stock Units 2026-10-13 4 M false 8333 D Common Shares 8333 0 D Each restricted stock unit represents a contingent right to receive one share of CRSP Common Shares. Amount reported represents the number of shares required to be sold by the reporting person to cover the tax withholding obligation in connection with the vesting of these restricted stock units. This sale is mandated by the Company's RSU Settlement Policy to fund the tax withholding obligation and does not represent a discretionary trade by the reporting person. This restricted stock unit award was granted on October 13, 2023 with respect to 25,000 Common Shares, with (i) one third of the shares vesting on October 13, 2024, (ii) one third of the shares vesting on October 13, 2025, and (iii) one third of the shares vesting on October 13, 2026. /s/ Elizabeth Ryland Waldinger, attorney-in-fact 2026-10-15