X0609 4 2026-10-12 0001645460 Cue Biopharma, Inc. CUE 0001725092 Lin Shao-Lee false C/O CUE BIOPHARMA, INC. 100 CHESTNUT STREET, SUITE 300 SOMERVILLE MA 02143 true true false false Chief Executive Officer 0 Common Stock 2026-10-12 4 S 0 10000 27.50 D 695995 D Common Stock 2026-10-12 4 S 0 1087 28.05 D 694908 D The sales reported represent shares sold pursuant to the Issuer's Company-Wide Policy and do not represent discretionary transactions by the Reporting Person. These sales were made automatically to satisfy mandatory tax withholding obligations through a "sell-to-cover" transaction in connection with the vesting and settlement of restricted stock units, and the Reporting Person did not exercise any control over the timing, price or number of shares sold. /s/ Shao-Lee Lin 2026-10-14