X0609 4 2026-10-15 0 0000879169 INCYTE CORP INCY 0001205703 CAGNONI PABLO J false 1801 AUGUSTINE CUT-OFF WILMINGTON DE 19803 0 1 0 0 President, Global Head of R&D 1 Common Stock 2026-10-15 4 M 0 839 71.93 A 184039 D Common Stock 2026-10-15 4 M 0 423 61.76 A 184462 D Common Stock 2026-10-15 4 M 0 455 61.18 A 184917 D Common Stock 2026-10-15 4 M 0 925 64.25 A 185842 D Common Stock 2026-10-15 4 S 0 2642 112.71 D 183200 D Employee Stock Option (right to buy) 71.93 2026-10-15 4 M 0 839 0 D 2035-01-16 Common Stock 839 17627 D Employee Stock Option (right to buy) 61.76 2026-10-15 4 M 0 423 0 D 2033-07-13 Common Stock 423 3802 D Employee Stock Option (right to buy) 61.18 2026-10-15 4 M 0 455 0 D 2034-01-17 Common Stock 455 4096 D Employee Stock Option (right to buy) 64.25 2026-10-15 4 M 0 925 0 D 2034-07-14 Common Stock 925 19431 D This includes an aggregate of 183,200 shares of common stock issuable pursuant to previously reported restricted stock units and earned performance stock units that have not vested. Beginning January 17, 2025, options become exercisable in 37 installments, with the first 25% vesting on July 15, 2025 and the remainder vesting monthly over three years. The July 14, 2023 options become exercisable in 37 installments, with the first 25% vesting after one year and the remainder vesting monthly over three years. Beginning January 18, 2024, options become exercisable in 37 installments, with the first 25% vesting on July 14, 2024 and the remainder vesting monthly over three years. The July 15, 2024 options become exercisable in 37 installments, with the first 25% vesting after one year and the remainder vesting monthly over three years. /s/ Elizabeth Feeney, Attorney-In-Fact 2026-10-19