X0609 4 2026-10-16 0 0001830214 Ginkgo Bioworks Holdings, Inc. DNA 0001845677 Kelly Jason R false C/O GINKGO BIOWORKS HOLDINGS 27 DRYDOCK AVENUE BOSTON MA 02210 1 1 0 0 See remarks 0 Class A Common Stock 2026-10-16 4 M 0 55694 A 148957 D Class A Common Stock 2026-10-16 4 M 0 25790 A 174747 D Class A Common Stock 2026-10-19 4 S 0 45682 10.143 D 129065 D Restricted Stock Units 2026-10-16 4 M 0 55694 D Class A Common Stock 55694 18564 D Restricted Stock Units 2026-10-16 4 M 0 25790 D Class A Common Stock 25790 283677 D Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's Class A Common Stock. Represents shares sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock and/or restricted stock units. Sales to cover tax withholding obligations in connection with the vesting of such securities do not represent discretionary trades by the Reporting Person. The Issuer's equity incentive plans allow the Issuer to require that satisfaction of tax withholding obligations be funded by a "sell to cover" transaction. The RSUs were approved by the Compensation Committee of the Board of Directors on July 28, 2026 and shall vest as follows: 75% vested on October 16, 2026 and 25% will vest on January 21, 2027. The RSUs were approved by the Compensation Committee of the Board of Directors on July 28, 2026 and shall vest in equal quarterly installments over the next 12 quarters. Chief Executive Officer & Founder /s/ Karen Tepichin, Attorney-in-Fact 2026-10-21