X0609 4 2026-10-20 0001645469 Monopar Therapeutics MNPR 0001727334 Robinson Chandler false 1000 SKOKIE BLVD SUITE 350 WILMETTE IL 60091 1 1 Chief Executive Officer 0 Common Stock 2026-10-20 4 F 0 597 92.59 D 104127 D Common Stock 62815 I See Footnote Represents additional shares withheld by the issuer to pay for the applicable withholding tax due to administrative error in connection with the vesting and settlement of 12,873 restricted stock units on June 30, 2026, as reported on a Form 4 filed July 2, 2026. Represents shares held by the Chandler D. Robinson Irrevocable Trust U/A dated May 20, 2020. /s/ Quan Vu, Attorney-in-fact 2026-10-20